Results 91 to 100 of about 2,149 (290)

The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos

Advanced Science, EarlyView.
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan, Yelian Yan, Yalin Liang, Kanghua Zhong, Zhican Fu, Xiaobo Wang, Chao Liu, Tao Huang, Keliang Wu   +8 more
wiley   +1 more source

Celebrating change in archives

Boletim do Arquivo da Universidade de Coimbra
This paper deals with a number of changes. The first is the new way of looking at and beyond the record, trying to read its tacit narratives of power and knowledge, and taking into account archivalterity, which refers to the acts of continuous and ...
Eric Ketelaar
doaj   +1 more source

Archival theory and oral history documents

, 1995
This study was undertaken to examine in which circumstances archival theory, method and practices may be applied to oral history documents, with regard to appraisal and arrangement and description procedures, and in which circumstances they may not ...
MacDonald, Wilma
core  

SDS‐CRISPR for Single‐Nucleotide Variant Detection

Advanced Science, EarlyView.
Structure‐disruption‐sensitive CRISPR (SDS‐CRISPR) converts structural instability into single‐nucleotide precision, thereby overcoming mismatch tolerance in canonical Cas12a and enabling versatile diagnostics across DNA, RNA, and microRNA targets. When applied to rapid IDH1 mutation detection for glioma genotyping and integrated with lateral‐flow ...
Xin Guan, Chong Guo, Jiongyu Zhang, Rui Yang, Yerramsetti Ramachandra, Chengyu Hou, Minjie Pei, Shuo Zhang, Kurt T. Schalper, Xingye Liu, Qian Wu, Ketan R. Bulsara, Changchun Liu   +12 more
wiley   +1 more source

El mundo atlántico en el océano de papel de los archivos nobiliarios españoles (ss. XVI-XIX)

Bajo Guadalquivir y Mundos Atlánticos, 2018
Los archivos nobiliarios españoles conservan un rico acervo documental sobre eldescubrimiento, conquista, colonización, gobierno, administración y los fluidos contactos de la metrópoli con el imperio ultramarino lusoespañol.
Miguel Fernando Gómez Vozmediano
doaj  

Searching, Exploring, and Analyzing Historical Letters and the Underlying Networks

Digital Humanities in the Nordic and Baltic Countries Publications
Historical letters in archives are typically stored in fonds, based on letter recipients. To analyze the correspondences of a correspondent x, one has to aggregate the received letters in x’s own fond with the letters in the fonds of the correspondents ...
Eero Hyvönen, Petri Leskinen, Henna Poikkimäki, Heikki Rantala, Rafael Leal, Jouni Tuominen, Senka ˇDrobac, Ossi Koho, Ilona Pikkanen, Hanna-Leena Paloposki   +9 more
doaj   +1 more source

A Dual‐Functional Biohybrid Nanorobot to Synergistically Eradicate Biofilm and Degrade Antibiotic Resistance Genes

Advanced Science, EarlyView.
A biohybrid nanorobot integrating lytic bacteriophage N4 with Pd nanozymes is developed for targeted eradication of multidrug‐resistant E. coli biofilms. Synergistic bacterial lysis and ROS‐mediated oxidation enable simultaneous biofilm removal and antibiotic resistance genes degradation, maintaining high efficacy in complex wastewater environments ...
Junzheng Zhang, Tong Dou, Luokai Wang, Jingxian Yang, Wenrui Wang, Shuaitian Guo, Xiangyu Li, Xuefang Huang, Yunlei Xianyu, Dongsheng Wang   +9 more
wiley   +1 more source

Experiential Learning as Archival Activation: Reflections on University of Calgary’s Student Archival Residency Project Phase One

Music archives hold unique value in understanding the process of creators and sparking creativity in new researchers through their exploration. The University of Calgary Archives and Special Collections preserves and shares the archives of prominent ...
Reed, Lelland, Reid, Laura, Iles, Shea, Jones, David   +3 more
core   +1 more source

Description of Engineering Artifacts and Archival Data: EAD meets VRA

, 2014
This paper describes the experience in the implementation of an archival description system based on XML standards: EAD, EAC-CPF and VRA. The system offers the capability of managing and publishing archival descriptions of historical engineering fonds ...
Eito-Brun, Ricardo
core   +1 more source