Results 81 to 90 of about 2,149 (290)

The Death of the Fonds and the Resurrection of Provenance: Archival Context in Space and Time

open access: yes, 2002
While the concepts of the fonds, respect des fonds, and provenance were initially useful in Canada to offset ad hoc approaches to arrangement and description, the intellectual reality of provenance and the physical reality of the records have become so ...
Millar, Laura
core  

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

open access: yesAdvanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv   +8 more
wiley   +1 more source

Halted by the Archive: The Impact of Excessive Archival Restrictions on Scholars

open access: yes, 2005
This article, written from the dual perspectives of a scholar and an archivist, considers the impact of excessive archival restrictions on scholars who seek access to primary material in order to ensure the integrity and accuracy of their research. Ruth
Michael Moir, Ruth Panofsky
core   +1 more source

NQO1‐Mediated Anoikis Resistance and Immune Evasion Define a High‐Risk Multi‐Omic Subtype for Precision Management of T1 High‐Grade Bladder Cancer

open access: yesAdvanced Science, EarlyView.
Multi‐omic profiling of T1 high‐grade bladder cancer identifies a high‐risk subtype (T1HG1) driven by NQO1, which couples anoikis resistance with immune evasion. NQO1 orchestrates macrophage–T cell crosstalk suppression via CXCL9 modulation. Pharmacological NQO1 inhibition with skullcapflavone II enhances cisplatin efficacy, representing a promising ...
Bin Guo   +20 more
wiley   +1 more source

Proximity Matters: Disability, Erasure & the Archival Bond of Natural History [PDF]

open access: yes, 2020
This critical archival studies dissertation examines the subtleties of disability in records by broadly asking “how can we tell a history of disability with little to no forms of archival evidence?” I attempt to answer this question by interrogating the ...
Brilmyer, Gracen Mikus
core  

INB3P: A Multi‐Modal and Interpretable Co‐Attention Framework Integrating Property‐Aware Explanations and Memory‐Bank Contrastive Fusion for Blood–Brain Barrier Penetrating Peptide Discovery

open access: yesAdvanced Science, EarlyView.
INB3P is a multimodal framework for blood–brain barrier‐penetrating peptide prediction under extreme data scarcity and class imbalance. By combining physicochemical‐guided augmentation, sequence–structure co‐attention, and imbalance‐aware optimization, it improves predictive performance and interpretability.
Jingwei Lv   +11 more
wiley   +1 more source

Introgressed Variation in TaMYB7‐A1 Drives Graded Dormancy and Climate‐Adaptive Pre‐Harvest Sprouting Resistance in Wheat

open access: yesAdvanced Science, EarlyView.
TaMYB7‐A1 directly activates TaABI5 to enhance ABA signaling and regulate ABA‐GA homeostasis, enforcing seed dormancy. Its superior allele, derived from wild einkorn introgression, harbors a MITE insertion that elevates expression and two amino acid substitutions that enhance transcriptional activity, collectively generating graded PHS resistance for ...
Hao Wang   +18 more
wiley   +1 more source

Women writing about women. Mercede Mundula’s documents in the University Library of Cagliari

open access: yesJLIS.it
The essay presents the life and documents of the Cagliari-born poet, essayist and writer Mercede Mundula (1890-1947). The documents were donated by her daughters to the University Library of Cagliari in 1997.
Rapetti Mariangela
doaj   +1 more source

Interdisciplinary approach in preservation, digitization and sharing of archival materials

open access: yes, 2019
National and state archives are important part of nations’ cultural heritage. Storage of archival materials serves not only as a means of testaments of the past preservation, but also allows sharing of archival contents to a wide spectrum of users ...
Zawada, Michał
core   +1 more source

Biolipid Film‐Fused Electrochemiluminescence for Multipurpose In Situ Bioassays

open access: yesAdvanced Science, EarlyView.
An ECL‐emissive, membrane‐interactive scaffold was fabricated, and facilely fused with natural and non‐native phospholipids into multifactorial mimicries of cytomembranes and vesicles for in vitro representative membrane‐process probing. Such a biointerface‐based, state‐sensitive ECL paradigm not only pinpointed proximal phenomena, including channeling
Jialiang Chen   +9 more
wiley   +1 more source

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