Results 101 to 110 of about 36,168 (305)

The WFCAM Science Archive

, 2007
We describe the WFCAM Science Archive (WSA), which is the primary point of access for users of data from the wide-field infrared camera WFCAM on the United Kingdom Infrared Telescope (UKIRT), especially science catalogue products from the UKIRT Infrared Deep Sky Survey (UKIDSS).
Hambly, N. C., Collins, R. S., Cross, N. J. G., Mann, R. G., Read, M. A., Sutorius, E. T. W., Bond, I. A., Bryant, J., Emerson, J. P., Lawrence, A., Stewart, J. M., Williams, P. M., Adamson, A., Dye, S., Hirst, P., Warren, S. J.   +15 more
openaire   +2 more sources

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

An assessment of the legal and regulatory framework supporting the implementation of the National Integrated Identity Management System (NIIMS) in Kenya

Data & Policy
This study sought to establish the elements that constitute comprehensive legal and regulatory landscape for successful digital identity system establishment and implementation. Subsequently, the study sought to assess whether these elements were present
Victor Kabata
doaj   +1 more source

Historiography and archival science

, 1999
Kako je u prvoj polovini 19. stoljeća kritička historiografija dobijala veće priznanje, historiografija je konačno počela pokazivati veći interes za aktivno gradivo.
Žontar, Jože, Jože Žontar
core  

The isolation of nucleic acids from fixed, paraffin-embedded tissues-which methods are useful when?

, 2007
Museums and pathology collections around the world represent an archive of genetic material to study populations and diseases. For preservation purposes, a large portion of these collections has been fixed in formalin-containing solutions, a treatment ...
Haselkorn, Tamara, Michael Bunce, Gilbert, M.T.P., Worobey, Michael, Worobey Michael, Marck Eric Van, Lucas, S.B., Eric Van Marck, Haselkorn Tamara, Worobey, M., Sanchez, J., Lucas Sebastian B., Haselkorn, T., Van Marck, E., Sanchez, Juan J, Sebastian B Lucas, Lucas, Sebastian B., Sanchez Juan J., Juan J Sanchez, Laurence D Jewell, M Thomas P Gilbert, Sanchez, Juan J., Jewell, Laurence D., Tamara Haselkorn, Gilbert M. Thomas P., Gilbert, M. Thomas P., Jewell, L., Lucas, Sebastian B, Jewell, Laurence D, Van Marck, Eric, Jewell Laurence D., Gilbert, M Thomas P, Bunce, M., Michael Worobey, Bunce Michael, Bunce, Michael   +35 more
core   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

The archival training in the post-custodial era, in accordance with a scientific-informational paradigm : the portuguese model

, 2006
After the French Revolution, Archivistics developed as an auxiliary science, in the scope of History and Positivism. By the end of 19th century, when the famous Manual of Dutch Archivists was published (1998), it started a disciplinary autonomy becoming ...
Ribeiro, Fernanda
core  

Science and Technology in the First World War : CENDARI Archival Research Guide

, 2016
CENDARI Archival Research GuideThe subject “Science and Technology in the First World War” has so far been treated from the perspective on inventions and the development of new weapons, and often the focus has been on the topic of chemical warfare at the
Morselli, Francesca, Lehmann, Jörg
core   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source