Results 131 to 140 of about 36,168 (305)
Advanced Science, EarlyView.We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang +11 more
wiley +1 more source
Atlanti +, 2019 In this paper the author is convinced that today is the time when archival science can be defined in detail or even redefined. In professional archival literature we can find many definitions of archival science, which we can accept or take knowledge of without problems.
openaire +2 more sources
Advanced Science, EarlyView.A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui +9 more
wiley +1 more source
Advanced Science, EarlyView.HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li +13 more
wiley +1 more source
Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean
Advanced Science, EarlyView.This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma +11 more
wiley +1 more source
Personal archives and the boundaries of the archival science
Gragoatá, 2005 The article discusses some particularities of personal archives, focusing archival science principles as a whole. Personal archives, due to the fact of being more susceptible to have their custody interrupted by the heirs and due to being constituted by materials related to personal interests of their owners, which mean that they cannot be generalized,
openaire +2 more sources
Advanced Science, EarlyView.THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu +10 more
wiley +1 more source
2nd National Forum of the Directiors of the Diocesan Archives in Poland
Archiwa, Biblioteki i Muzea Kościelne, 2015 Waldemar Witold Żurek
doaj +1 more source
Bibliographies on archival science and records management
, 2017 "Hello! I am listing bibliographies on archival science and records management. Below is my list. If you know other bibliographies please let me know. Many thanks in advance :) Paper: 1. J. Pakulski, R. Piechota, B.
Klaus Graf
core
The evolution of archives and knowledge in archival science
Revista Ibero-Americana de Ciência da Informação, 2013 Reflexão descritiva, fundamentada em pesquisa bibliográfica, sobre a evolução dos arquivos e do conhecimento em arquivologia. Trata da epistemologia do conhecimento, buscando evidenciar a epistemologia em arquivologia. Destaca as abordagens cronológicas difundidas na literatura arquivística para dar suporte ao estudo da história dos arquivos e do ...
openaire +1 more source