Results 41 to 50 of about 288,588 (293)

Scheduling unit processing time arc shutdown jobs to maximize network flow over time: complexity results

open access: yes, 2013
We study the problem of scheduling maintenance on arcs of a capacitated network so as to maximize the total flow from a source node to a sink node over a set of time periods.
Boland, Natashia   +3 more
core   +1 more source

Effect of COVID-19 and other determinants on the reduction of non-urgent emergency department access in North-East Italy: does supply affect demand?

open access: yesResearch in Health Services & Regions
This study examines the impact of the COVID-19 pandemic on non-urgent emergency department (ED) utilizzation in Friuli Venezia Giulia, Italy, comparing the pre-COVID (2019) and COVID (2021) periods. A retrospective observational analysis at the municipal
Michele Gobbato   +4 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Broadband Photometry of 105 Giant Arcs: Redshift Constraints and Implications for Giant Arc Statistics

open access: yes, 2011
We measure the photometric properties of 105 giant arcs that were identified in systematic searches for galaxy-cluster-scale strong lenses in the Second Red-Sequence Cluster Survey (RCS-2) and the Sloan Digital Sky Survey (SDSS).
Abazajian   +51 more
core   +1 more source

ARC syndrome [PDF]

open access: yesThe Turkish Journal of Pediatrics, 2017
Arthrogryposis-renal dysfunction-cholestasis (ARC) is an autosomal recessive multisystem disorder characterized by arthrogryposis, renal tubular dysfunction and neonatal cholestasis with low gamma glutamyl transpeptidase activity. Most of the mutations in ARC syndrome are associated with the vacuolar protein sorting 33B (VPS33B) gene on chromosome ...
Mehmet Mutlu   +5 more
openaire   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Friedel oscillations due to Fermi arcs in Weyl semimetals

open access: yes, 2012
Weyl semimetals harbor unusual surface states known as Fermi arcs, which are essentially disjoint segments of a two dimensional Fermi surface. We describe a prescription for obtaining Fermi arcs of arbitrary shape and connectivity by stacking alternate ...
A. Kitaev, G. Volovik, Pavan Hosur
core   +1 more source

New Applied Problems in the Theory of Acyclic Digraphs

open access: yesMathematics, 2021
The following two optimization problems on acyclic digraph analysis are solved. The first of them consists of determining the minimum (in terms of volume) set of arcs, the removal of which from an acyclic digraph breaks all paths passing through a subset
Gurami Tsitsiashvili, Victor Bulgakov
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Imagining circles: empirical data and a perceptual model for the arc-size illusion [PDF]

open access: yes, 2016
An essential part of visual object recognition is the evaluation of the curvature of both an object's outline as well as the contours on its surface. We studied a striking illusion of visual curvature--the arc-size illusion (ASI)--to gain insight into ...
Kingdom, Frederick A.A.   +3 more
core   +2 more sources

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