Results 131 to 140 of about 273,435 (319)

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

CAFF Technical Report No.2 - Human Disturbance at Arctic Seabird Colonies [PDF]

open access: yes, 1998
Human Disturbance at Arctic Seabird Colonies is the Arctic Council's CAFF Working Group's Technical Report No.2, published 1998.
Arctic Council , Conservation of Arctic Flora and Fauna Working Group
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

CAFF Habitat Conservation Report No.8 - A Summary of Legal Instruments and National Frameworks for Arctic Marine Conservation [PDF]

open access: yes, 2000
A Summary of Legal Instruments and National Frameworks for Arctic Marine Conservation is Arctic Council's CAFF Working Group's Habitat Conservation Report No.8, published ...
Arctic Council , Conservation of Arctic Flora and Fauna Working Group
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

CAFF Habitat Conservation Report No.3 - National Mechanisms and Principles for Protected Areas in the Arctic Countries [PDF]

open access: yes, 1996
National Mechanisms and Principles for Protected Areas in the Arctic Countries is the Arctic Council's CAFF Working Group's Habitat Conservation Report No.3, published 1996. The Report is part of the CAFF's Circumpolar Protected Area Network (CPAN)Expert
Arctic Council , Conservation of Arctic Flora and Fauna Working Group
core  

Russia – Arctic

open access: yes
Russia is the largest Arctic country, with a territory covering more than half of the Arctic Ocean coastline and 2.5 million Arctic inhabitants. The Arctic constitutes an integral element of Russia's identity, economic development, military and environmental security.
openaire   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

CAFF Technical Report No.7 - Workshop On Seabird Incidental Catch In The Waters Of Arctic Countries [PDF]

open access: yes, 2000
Incidental catch of seabirds in fisheries is an issue common to nations fishing in the waters of Arctic Countries. This Workshop brought together a variety of experts from Conservation of Arctic Flora and Fauna (CAFF) countries, and others, to exchange
Arctic Council , Conservation of Arctic Flora and Fauna Working Group
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

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