Results 31 to 40 of about 147,760 (311)
Climigration? Population and climate change in Arctic Alaska [PDF]
, 2016 Residents of towns and villages in Arctic Alaska live on “the front line of climate change.” Some communities face immediate threats from erosion and flooding associated with thawing permafrost, increasing river flows, and reduced sea ice protection of ...
Hamilton, Lawrence C. +4 more
core +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Det arktiske samarbeidet sett fra Sápmi: Samerådets perspektiv på Arktisk råd – og veien fremover
Internasjonal PolitikkArktisk råd er et unikt mellomstatlig samarbeid der seks urfolksorganisasjoner har plass ved bordet som permanente deltagere. Urfolk i Arktis etablerte et samarbeid tidlig på 1970-tallet og var klare for å kreve en plass ved bordet da statene i Arktis ...
Per Olof Nutti
doaj +1 more source
The Arctic council as an international organization of a new type
Международная аналитика, 2017 The article emphasizes that the Arctic Council (AC) is a high level forum of cooperation, based on taking decisions by consensus that are carried out by member states on a voluntary basis and in accordance with their national interests.
L. S. Voronkov, A. A. Smirnova
doaj +1 more source
Assessments in Policy-Making: Case Studies from the Arctic Council [PDF]
, 2014 Julkaistu ...
Banul, Karolina +5 more
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Thawing Out: The Role of the Arctic Council Service in a Melting Arctic [PDF]
, 2016 With the changing natural and political climate of the Arctic, conflicts over resource extraction and navigation will become inevitable. Empowering an intergovernmental institution like the Arctic Council Service may be the only solution.
Enos, Taylor J
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
The need to know: governing a region and its economy [PDF]
, 2015 This paper investigates the ways in which the economy has been incorporated into the political reasoning and practice of region-building in the Barents Region among experts.
Tennberg, Monica
core +3 more sources
Sustainable Development, Natural Resource Extraction, and the Arctic: The Road Ahead [PDF]
, 2016 Sustainable development has emerged as an integral nexus, linking together critically important global issues including environmental stewardship and economic growth. Understanding sustainable development demands a close analysis of evolving definitions,
Canuel, Edward
core +1 more source