Results 51 to 60 of about 1,963,224 (195)

TROMSØ DECLARATION On the occasion of the Sixth Ministerial Meeting of The Arctic Council April, 2009 [PDF]

open access: yes, 2009
TROMSØ DECLARATION On the occasion of the Sixth Ministerial Meeting of The Arctic Council.
Arctic Council, -
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Har Arktisk råd noen betydning?

open access: yesInternasjonal Politikk
Artikkelen er en personlig vurdering av betydningen til Arktisk råd etter å ha vært såkalt SAO Chair i to år. Abstract in English Does the Arctic Council Matter?
Morten Høglund
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Senior Arctic Official (SAO) Report to Ministers, Nuuk Greenland, 2011 [PDF]

open access: yes, 2011
Arctic Council Senior Arctic Officials' (SAO) Report to Ministers.
Arctic Council, -
core   +1 more source

Russia’s Security Perceptions and Arctic Governance

open access: yesPolitics and Governance
Russia’s war in Ukraine further strained Russia’s relations with the West and negatively influenced Arctic regional governance, especially after seven members of the Arctic Council paused cooperation with Russia.
Angela Borozna
doaj   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

Internationalization of Vocational Education in the Arctic Council Member-States’ Universities

open access: yesАрктика и Север, 2020
Nowadays, the potential for international cooperation in the Arctic is concentrated within the framework of such an influential international structure as the Arctic Council, where Russia is presiding over soon in 2021–2023.
Maria A. PITUKHINA
doaj   +1 more source

China, Republic of Korea and Japan in the Arctic: politics, economy, security [PDF]

open access: yesАрктика и Север, 2016
China, South Korea and Japan are actively pursuing scientific, economic and political activities for the development of the Arctic, the Arctic resources, ensure security in it, seeking to increase its role in the Arctic Council, cooperating and competing-
Valeriy P. Zhuravel
doaj   +1 more source

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