Results 61 to 70 of about 1,819,606 (286)

China, Republic of Korea and Japan in the Arctic: politics, economy, security [PDF]

open access: yesАрктика и Север, 2016
China, South Korea and Japan are actively pursuing scientific, economic and political activities for the development of the Arctic, the Arctic resources, ensure security in it, seeking to increase its role in the Arctic Council, cooperating and competing-
Valeriy P. Zhuravel
doaj   +1 more source

Becoming an Arctic Council NGO observer [PDF]

open access: yesPolar Record, 2018
AbstractThis paper explores the question: How is the NGO observer application process to the Arctic Council influenced by perceptions of legitimacy of the applicant? Using information gleamed from numerous interviews we map out the application process for NGO observer status in the Arctic Council.
Burke, Danita Catherine   +1 more
openaire   +2 more sources

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Senior Arctic Official (SAO) Report to Ministers, Tromsø Norway, 2009 [PDF]

open access: yes, 2009
Arctic Council Senior Arctic Officials' (SAO) Report to Ministers.
Arctic Council, -
core   +1 more source

Russia’s Security Perceptions and Arctic Governance

open access: yesPolitics and Governance
Russia’s war in Ukraine further strained Russia’s relations with the West and negatively influenced Arctic regional governance, especially after seven members of the Arctic Council paused cooperation with Russia.
Angela Borozna
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Arctic Climate Impact Assessment - Policy Document [PDF]

open access: yes, 2004
Arctic Climate Impact Assessment - Policy Document.
Arctic Council, -
core   +1 more source

Samfundssikkerhed i Arktis – en ny dagsorden for Arktisk Råd?

open access: yesInternasjonal Politikk
Arktisk Råd, og dets arbejdsgruppe Emergency Prevention, Preparedness and Response (EPPR) og det uafhængige Arctic Coast Guard Forum (ACGF) udgør de otte arktiske staters væsentligste organer for samarbejde vedrørende beredskab. Dog beskæftiger ingen af
Rasmus Dahlberg   +1 more
doaj   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

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