Results 61 to 70 of about 147,760 (311)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Russia’s Security Perceptions and Arctic Governance

Politics and Governance
Russia’s war in Ukraine further strained Russia’s relations with the West and negatively influenced Arctic regional governance, especially after seven members of the Arctic Council paused cooperation with Russia.
Angela Borozna
doaj   +1 more source

Internationalization of Vocational Education in the Arctic Council Member-States’ Universities

Арктика и Север, 2020
Nowadays, the potential for international cooperation in the Arctic is concentrated within the framework of such an influential international structure as the Arctic Council, where Russia is presiding over soon in 2021–2023.
Maria A. PITUKHINA
doaj   +1 more source

China, Republic of Korea and Japan in the Arctic: politics, economy, security [PDF]

Арктика и Север, 2016
China, South Korea and Japan are actively pursuing scientific, economic and political activities for the development of the Arctic, the Arctic resources, ensure security in it, seeking to increase its role in the Arctic Council, cooperating and competing-
Valeriy P. Zhuravel
doaj   +1 more source

Preferences, Perceptions, and Veto Players: Explaining Devolution Negotiation Outcomes in the Canadian Territorial North [PDF]

, 2012
Since the early part of the 20th century, the federal government has engaged in a long and slow process of devolution in the Canadian Arctic. Although the range of powers devolved to the territorial governments has been substantial over the years, the ...
Abele, Abele, Bone, Cameron, Cameron, Chretien, Christopher Alcantara, Clancy, Coates, Coates, Dacks, Dacks, Dickerson, Feehan, Henderson, King, Mayer, Michael, Morrison, O'Brien, Smyth, White, Zaslow   +22 more
core   +2 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Fate Control and Human Rights: The Policies and Practices of Local Governance in America's Arctic [PDF]

, 2014
The loss of territoriality over lands conveyed under the Alaska Native Claims Settlement Act had adverse impacts for Alaskan tribal governance. Despite policy frameworks that emphasize the value of local governance at an international, regional, and ...
Kimmel, Mara
core   +1 more source

Bacterial genomics reveal the complex epidemiology of an emerging pathogen in Arctic and boreal ungulates [PDF]

, 2016
Northern ecosystems are currently experiencing unprecedented ecological change, largely driven by a rapidly changing climate. Pathogen range expansion, and emergence and altered patterns of infectious disease, are increasingly reported in wildlife at ...
Amanda Niptanatiak, Brett T. Elkin, Bryan J. Macbeth, Cait Nelson, Frank Van Der Meer, Helen M. Schwantje, Jeroen De Buck, Karin Orsel, Laura Finnegan, Layne G. Adams, Mathieu Dumond, Roman Biek, Ruth Nicolet Zadoks, Shane Sather, Susan J. Kutz, Sylvia L. Checkley, Taya L. Forde, Taya L. Forde, Tracy Davison   +18 more
core   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Little Fish, Big Pond: Icelandic Interests and Influence in Arctic Governance

Nordicum-Mediterraneum, 2016
The paper presents the Arctic Council and Iceland’s role within it before turning to issues that are governed outside of the Arctic Council system, in particular, Arctic fisheries and maritime boundaries.
Rachael L. Johnstone
doaj