Results 41 to 50 of about 132,168 (301)

Human infectious diseases and the changing climate in the Arctic

open access: yesEnvironment International, 2018
Climatic factors, especially temperature, precipitation, and humidity play an important role in disease transmission. As the Arctic changes at an unprecedented rate due to climate change, understanding how climatic factors and climate change affect ...
Audrey Waits   +4 more
doaj   +1 more source

The aerocrew mission : training space Session at Ny Aalesund Arctic base [PDF]

open access: yes, 2008
The Aerocrew mission has been realized in December 2007, in the frame of the International Polar Year, and in cooperation with the Polar Institut Paul-Émile Victor.
Apel, Uwe   +2 more
core  

Psychological adaptation to extreme environments: Antarctica as a space analogue [PDF]

open access: yes, 2018
Space analogues are settings where particular conditions can be reproduced to study physiological and psychological variables experienced in space. Antarctica is one of the most reliable analogues to assess the effects of isolation, confinement, light ...
Barbarito, Marta   +5 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

No improvement of sleep from vitamin D supplementation: insights from a randomized controlled trial

open access: yesSleep Medicine: X, 2021
Background: Vitamin D has been linked to sleep health in observational studies. Data from randomized controlled trials (RCTs) with vitamin D is scarce.
A.U. Larsen   +3 more
doaj   +1 more source

Occasional Publications on Northern Life, No. 04 [PDF]

open access: yes, 1983
The need to exchange information on research in reindeer and caribou diseases became apparent to investigators attending the Second International Reindeer/Caribou Symposium in Roros, Norway, in 1979.
Dieterich, Robert A., Morton, Jamie K.
core  

Legacy pollutants are declining in Great Skuas (Stercorarius skua) but remain higher in Faroe Islands than in Scotland [PDF]

open access: yes, 2016
To monitor environmental pollutants in Faroese biota, samples from a top predator were analysed and put into a spatial and temporal context. Analysis of 20 Great Skua eggs sampled in 2012 from the Faroe Islands showed >70 % lower concentrations of ...
Alonso, Sarah   +5 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

2019 State-of-the-Science of Dispersants and Dispersed Oil (DDO) in U.S. Arctic Waters: Public Health and Food Safety [PDF]

open access: yes, 2019
Chemical dispersants were employed on an unprecedented scale during the Deepwater Horizon oil spill in the Gulf of Mexico, and could be a response option should a large spill occur in Arctic waters. The use of dispersants in response to that spill raised
Coastal Response Research Center
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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