Results 51 to 60 of about 63,512 (302)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Medicine Story: Secret Life of the Arctic Willow
, 2023 The medicine story about the Arctic Willow told through the eyes of three little girls living in the Canadian ...
Haramincic, Arijana
core
, 2023 The Arctic mutation, encoding E693G in the amyloid precursor protein (APP) gene [E22G in amyloid-β (Aβ)], causes dominantly inherited Alzheimer’s disease. Here, we report the high-resolution cryo-EM structures of Aβ filaments from the frontal cortex of a
Schweighauser, Manuel +16 more
core +1 more source
Centre for Arctic Medicine, Thule Institute, University of Oulu, Finland [PDF]
International Journal of Circumpolar Health, 2004 Centre for Arctic Medicine (CAM) is part of Thule Institute, University of Oulu. The CAM has its origins in the Nordic Secretariat of Arctic Medicine founded in 1969, which was integrated into the structure of the University of Oulu in 1996 and became a part of the Thule Institute in 2001.
openaire +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
MercuNorth – monitoring mercury in pregnant women from the Arctic as a baseline to assess the effectiveness of the Minamata Convention [PDF]
, 2021 Exposure to mercury (Hg) is a global concern, particularly among Arctic populations that rely on the consumption of marine mammals and fish which are the main route of Hg exposure for Arctic populations.The MercuNorth project was created to establish ...
Eva C. Bonefeld-Jørgensen +59 more
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BMJ Open Gastroenterology, 2019 Background It remains unclear whether or which prediagnostic lifestyle and dietary factors influence colorectal cancer (CRC) survival following diagnosis.
Guri Skeie +3 more
doaj +1 more source
No improvement of sleep from vitamin D supplementation: insights from a randomized controlled trial
Sleep Medicine: X, 2021 Background: Vitamin D has been linked to sleep health in observational studies. Data from randomized controlled trials (RCTs) with vitamin D is scarce.
A.U. Larsen +3 more
doaj +1 more source
O MEDICINES IN THE ARCTIC DISTRICTS OF THE SAKHA REPUBLIC (YAKUTIA)
Север и рынок: формирование экономического порядка, 2023 Access to medicines is intrinsically linked to fundamental human rights to health and life. The need to make medicines more accessible is articulated in strategic planning documents, including the Strategy for the Development of the Arctic Zone of the Russian Federation and National Security until 2035.
Sardana M. Tarabukina +1 more
openaire +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source