Results 111 to 120 of about 2,560,874 (291)

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay   +15 more
wiley   +1 more source

CAFF Technical Report No.4 - Global Overview of the Conservation of Arctic Migratory Breeding Birds Outside the Arctic [PDF]

open access: yes, 1998
Global Overview of the Conservation of Arctic Migratory Breeding Birds Outside the Arctic is the Arctic Council's CAFF Working Group's Technical Report No.4, published ...
Arctic Council , Conservation of Arctic Flora and Fauna Working Group
core   +1 more source

Planning and implementation of a community-wide tuberculosis screening intervention: a case study from Naujaat, Nunavut, Canada

open access: yesInternational Journal of Circumpolar Health
In Nunavut, public health management of tuberculosis (TB) remains a challenge due to social and economic inequities, geographic isolation, TB-related stigma, and distrust in healthcare linked to a history of colonialism.
Xiao-Ting Xie   +6 more
doaj   +1 more source

Arctic Ocean Acidification Assessment: Summary for Policymakers [PDF]

open access: yes, 2013
Executive summary of the 2013 Arctic Ocean Acidification Assessment, including an update on the state of ocean acidification in the Arctic and how that acidification is impacting on the Arctic marine environment. It outlines each of the ten key findings
Arctic Monitoring and Assessment Programme
core  

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab   +19 more
wiley   +1 more source

Arctic Marine Shipping Assessment 2009 [PDF]

open access: yes, 2009
The Arctic is undergoing extraordinary transformations early in the 21st century. Natural resource development, governance challenges, climate change and marine infrastructure issues are influencing current and future marine uses of the Arctic.
Arctic Council, Protection of the Arctic Marine Environment (PAME)
core  

Health Care Use Among Patients Presenting to Emergency Department for Gout Flares in Ontario, Canada: A Population‐Based Health Systems Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective We characterized emergency department (ED) gout visits and identified patient characteristics and health services patterns contributing to ED presentations. Methods We conducted a population‐based study of ED gout visits in Ontario, Canada, between 2014 and 2023.
Timothy S. H. Kwok   +7 more
wiley   +1 more source

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