Results 51 to 60 of about 226,222 (357)

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

Preparing for a Northwest Passage: A Workshop on the Role of New England in Navigating the New Arctic [PDF]

, 2018
Preparing for a Northwest Passage: A Workshop on the Role of New England in Navigating the New Arctic (March 25 - 27, 2018 -- The University of New Hampshire) paired two of NSF\u27s 10 Big Ideas: Navigating the New Arctic and Growing Convergence ...
Ashcraft, Catherine M, Brewer, Jennifer F, Burakowski, Elizabeth, Coffin, Jaed M, Dibb, Jack E, Duderstadt, Katharine A, Hamilton, Lawrence C, Kinner, Nancy E, Mayer, Larry A., Miksis-Olds, Jennifer L, Salisbury, Joseph, Seger, Kerri D, Varner, Ruth K., Wake, Cameron P.   +13 more
core   +1 more source

The Dynamics of Intra-jurisdictional Relations in the Inuit Regions of the Canadian Arctic: An Institutionalist Perspective [PDF]

, 2013
One of the most exciting developments in Canadian federalism has been the emergence of Aboriginal self-governing regions. This paper constructs a theoretical framework for exploring the evolution of intra-jurisdictional relations in the self-governing ...
Alcantara, Christopher, Wilson, Gary N.
core   +3 more sources

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Tourism Opportunities for Residents of the Russian Arctic: Within the Region, in Russia and Abroad

Регионология
Introduction. Russian Arctic regions have a significant tourism potential, but it is not fully realized. The purpose of the study is to assess the possibilities of the population of the Arctic regions of the Russian Federation to realize tourism in their
Svetlana V. Kondrateva, Valentina V. Karginova-Gubinova, Marina V. Moroshkina   +2 more
doaj   +1 more source

Fossil Floras of the Arctic Regions [PDF]

Nature, 1878
THE author of the valuable paper communicated in NATURE, vol xix. p. 124, on “The Fossil Floras of the Arctic Regions”, will find in an essay of mine, entitled “Thalassa”, and published in the course of last year, a number of facts and arguments in corroboration of his views regarding the influence of oceanic currents upon climate. In this essay, which
openaire   +2 more sources

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

The arctic curve of the domain-wall six-vertex model

, 2009
The problem of the form of the `arctic' curve of the six-vertex model with domain wall boundary conditions in its disordered regime is addressed. It is well-known that in the scaling limit the model exhibits phase-separation, with regions of order and ...
A. G. Pronko, A. Okounkov, A.G. Izergin, A.G. Izergin, D. Allison, D. Zeilberger, D.M. Bressoud, F. Colomo, F. Colomo, F. Colomo, F. Colomo, F. Colomo, F.R. Gantmacher, G. Kuperberg, H. Cohn, H. Cohn, J. Ambjorn, J. Propp, K. Eloranta, K. Johansson, K. Johansson, L. Paniak, L.A. Takhtadjan, M.E. Fisher, N. Elkies, N. Kitanine, N.M. Bogoliubov, N.M. Bogoliubov, O.F. Syljuåsen, P. Bleher, P. Zinn-Justin, P.L. Ferrari, P.L. Ferrari, R. Cerf, R. Kenyon, R. Kenyon, R.C. Penner, R.J. Baxter, S.V. Kerov, V.E. Korepin, V.E. Korepin, V.E. Korepin   +41 more
core   +3 more sources

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

Innovation Potential of the Arctic Regions of Russia

Арктика и Север, 2022
The paper provides a comparative analysis of foreign and Russian methodologies for assessing innovation potential. It is shown that foreign methodologies cannot be used to determine the innovation potential of the Arctic regions of Russia due to specific
Vyacheslav A. Tsukerman , Elena S. Goryachevskaya   +1 more
doaj   +1 more source