Results 71 to 80 of about 2,560,874 (291)

THE RADIO WAVES PROPAGATION CHARACTERISTICS IN THE GLIDESLOPE AXES OF THE GROUND CONTROLLED APPROACH SYSTEMS IN THE ARCTIC REGIONS

open access: yesНаучный вестник МГТУ ГА, 2016
Information about the location of the aircraft, with a decrease along a predetermined path, the carriages, the floor-fer with the use of radio landing systems.
G. S. Nakhmanson   +2 more
doaj  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

STRUCTURAL SHIFTS IN THE ARCTIC ECONOMY DRIVEN BY THE SPILLOVER OF INVESTMENT DEMAND ACROSS INDUSTRIES

open access: yesСевер и рынок: формирование экономического порядка
Under financial constraints, the formulation of structural and investment policies in the Arctic regions must account for investment flows between industries. This highlights the importance of analyzing structural shifts within economic systems resulting
Vladimir N. Myakshin   +3 more
doaj   +1 more source

Exploration of the Arctic Regions [PDF]

open access: yesProceedings of the Royal Geographical Society of London, 1874
n ...
openaire   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

MANAGING HOUSEHOLD FINANCIAL SECURITY IN THE RUSSIAN ARCTIC

open access: yesСевер и рынок: формирование экономического порядка
Household financial security management is a key factor in ensuring the socio-economic sustainability of the Russian Arctic regions, which are characterized not only by their strategic importance and resource potential but also by increased vulnerability
Anastasia N. Chapargina
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

The second year of pandemic in the Arctic: examining spatiotemporal dynamics of the COVID-19 "Delta wave" in Arctic regions in 2021. [PDF]

open access: yesInt J Circumpolar Health, 2022
Tiwari S   +7 more
europepmc   +1 more source

Masters Students' Perceptions of Distance and Transport Options

open access: yesEducation in the North, 2018
This article is situated within the Arctic Regions North Norway and North/East Iceland. It presents a study on what motivates adults in Arctic regions to apply for and complete a Master’s degree in Education.
Mirjam Harkestad Olsen   +1 more
doaj   +1 more source

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