Results 51 to 60 of about 50,296 (313)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Immigration, Community Integration and Public Health in Colorado's Rocky Mountains: An Overview and its Governance

open access: yesJournal of Rural and Community Development, 2015
This paper explores the link between new immigration to Colorado (USA) mountain communities and public health service access with a case study focus on Lake County, Colorado. It utilizes a combination of key informant interviews—with county commissioners,
Matthew T Klick
doaj  

Coastal marine biodiversity in the western Canadian Arctic

open access: yesArctic Science, 2022
Establishing a baseline of Arctic marine biodiversity is necessary for monitoring impacts of climate change in the vulnerable Canadian Arctic and protecting sensitive regions that are of significant importance to Inuit culture and socioeconomics.
Miranda Bilous   +2 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

Northern Research Reports [PDF]

open access: yes, 1948
A report titled "Medical Investigation of Southampton Island" by Malcolm Brown is followed by 28 reports on research projects that were in progress at the end of 1948 and that were funded in part or in whole by the Arctic Institute. The 3 anthropological
North America, Arctic Institute of
core   +1 more source

The Arctic Region and Its Inhabitants [PDF]

open access: yes
There are numerous definitions of the Arctic according to the One Health concept, which adopts a broad, holistic approach to the health of humans, wildlife, and the environment.
Emelyanova, Anastasia
core   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

Pan-arctic trends in terrestrial dissolved organic matter from optical measurements [PDF]

open access: yes, 2016
Climate change is causing extensive warming across arctic regions resulting in permafrost degradation, alterations to regional hydrology, and shifting amounts and composition of dissolved organic matter (DOM) transported by streams and rivers.
Tank, Suzanne   +38 more
core   +1 more source

Basic Income as a Measure of Social Support in the Arctic Regions of the Russian Federation: Statement of the Problem

open access: yesАрктика и Север
The Arctic zone of the Russian Federation is one of the most promising resource and logistics regions of the state. A significant challenge to its development is the low population density, which hinders the development of necessary infrastructure and ...
Denis A. Novikov
doaj   +1 more source

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