Results 51 to 60 of about 2,560,874 (291)
The Arctic Council Iqaluit 1998 Ministerial Meeting [PDF]
, 1998 The Ministerial Declaration from the 1st Arctic Council Ministerial Meeting in Iqaluit, 18 September ...
Arctic Council, -
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Arctic Environmental Protection Strategy (AEPS) Ministerial Meeting in Alta, Norway. 1997 [PDF]
, 1997 Arctic Environmental Protection Strategy (AEPS) is the predecessor of the Arctic Council, established in Rovaniemi Finland in 1991.
Arctic Council, -
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Declaration on the Establishment of the Arctic Council 1996 - Ottawa Declaration. [PDF]
, 1996 Declaration on the Establishment of the Arctic Council - Joint Communique of the Governments of the Arctic Countries on the Establishment of the Arctic Council.
Arctic Council, -
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Regional variability of a projected sea ice‐free Arctic during the summer months
Geophysical Research Letters, 2016 Climate projections of sea ice retreat under anthropogenic climate change at the regional scale and in summer months other than September have largely not been evaluated.
F. Laliberté +2 more
doaj +1 more source
Модернизация, инновация, развитие, 2016 This article discusses the use of balance of labour resources and population and labour resources movements balance for the assessment of the current and future state of regional labor markets and migration linkages in the regions of the Russian Arctic ...
A. G. Korovkin +3 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Implementation and Effectiveness of Antiretroviral Therapy in Greenland
Emerging Infectious Diseases, 2008 Analyses from the Danish HIV Cohort Study showed that, despite comparable economic means and general education of healthcare personnel, antiretroviral treatment of HIV in Greenland began later and has been implemented at a slower pace with lower ...
Nicolai Lohse +2 more
doaj +1 more source