Results 41 to 50 of about 2,013 (255)

Future emissions from shipping and petroleum activities in the Arctic [PDF]

Atmospheric Chemistry and Physics, 2011
The Arctic sea-ice is retreating faster than predicted by climate models and could become ice free during summer this century. The reduced sea-ice extent may effectively "unlock" the Arctic Ocean to increased human activities such as transit shipping and
G. P. Peters, T. B. Nilssen, L. Lindholt, M. S. Eide, S. Glomsrød, L. I. Eide, J. S. Fuglestvedt   +6 more
doaj   +1 more source

Large Vessel Activity and Low-Frequency Underwater Sound Benchmarks in United States Waters

Frontiers in Marine Science, 2021
Chronic low-frequency noise from commercial shipping is a worldwide threat to marine animals that rely on sound for essential life functions. Although the U.S.
Samara M. Haver, Samara M. Haver, Jeffrey D. Adams, Leila T. Hatch, Sofie M. Van Parijs, Robert P. Dziak, Joseph Haxel, Scott A. Heppell, Megan F. McKenna, David K. Mellinger, David K. Mellinger, Jason Gedamke   +11 more
doaj   +1 more source

SAV1 in Cooperation With FKBP52 Participates in Implantation

Advanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao, Yafang Lu, Zhaoyu Jia, Junxiang Ren, Ziyi Ge, Xinyu Liu, Hui Zhao, Zi‐Jiang Chen, Junhao Yan, Wei Wang, Jia Yuan   +10 more
wiley   +1 more source

Projected changes to Arctic shipping routes after stratospheric aerosol deployment in the ARISE-SAI scenarios

Frontiers in Climate
IntroductionRapid reductions in Arctic sea ice in response to warming have led to increased interest in using the Arctic Ocean for commercial shipping. As the world warms, however, different strategies are being considered to stabilize or reduce surface ...
Ariel L. Morrison, Debanjali Pathak, Elizabeth A. Barnes, James W. Hurrell   +3 more
doaj   +1 more source

Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis

Advanced Science, EarlyView.
Genomic amplification drives aberrant nuclear localization of IDH3A in melanoma. Independent of its canonical metabolic activity, nuclear IDH3A cooperates with YBX1 to activate the c‐JUN/c‐FOS transcriptional program, while NONO facilitates its nuclear localization.
Juan Ran, Yanchun Fang, Shengming Ruan, Juling Wang, Songbai Liu, Yuan Mao, Dongsheng Hou, Yanping Wang, Zi Ye, Qiong Li, Daoxiang Zhang   +10 more
wiley   +1 more source

Evolutionary game analysis of Arctic shipping black carbon emission reduction strategies based on government regulation and port fee differential policies

Humanities & Social Sciences Communications
The issue of black carbon (BC) emissions from Arctic shipping has garnered significant attention from the international community. Promoting action among key stakeholders is particularly critical at this juncture.
Xinli Qi, Zhenfu Li, Yiran Zhang, Qiqi Zhang, Chunrui Song   +4 more
doaj   +1 more source

Cost–Benefit Analysis of a Trans-Arctic Alternative Route to the Suez Canal: A Method Based on High-Fidelity Ship Performance, Weather, and Ice Forecast Models

Journal of Marine Science and Engineering, 2023
Climate change in recent years has produced viable shipping routes in the Arctic. However, critical uncertainties related to maritime operations in the Arctic make it difficult to predict ship speeds in ice and, thus, the voyage time and fuel costs. Cost–
Zhiyuan Li, Li Ding, Luofeng Huang, Jonas W. Ringsberg, Hui Gong, Nicolas Fournier, Zhenju Chuang   +6 more
doaj   +1 more source

Degrading GPX4 via Biomimetic Nanoparticle‐Mediated In Situ Synthesis of Deep‐Learning‐Designed Binder‐Degron Chimeras for Prostate Cancer Therapy

Advanced Science, EarlyView.
A deep‐learning‐designed binder is fused to a combinatorial degron to create a binder‐degron chimera (bdC) that recruits the CUL2‐RING ubiquitin ligase complex. Encapsulation in a prostate‐cancer‐targeted, CD47‐camouflaged nanocarrier enables tumor‐specific in situ bdC expression, triggering GPX4 degradation and ferroptosis, thereby establishing a ...
Si‐Han Zhang, Ye An, Na Zeng, Mei‐Cheng Liu, Jian‐Xuan Sun, Xi Gong, Jin‐Zhou Xu, Shao‐Gang Wang, Qi‐Dong Xia   +8 more
wiley   +1 more source

Exploring decarbonization priorities for sustainable shipping: A natural language processing-based experiment

Sustainable Futures
The shipping industry is currently the sixth largest contributor to global emissions, responsible for one billion tons of greenhouse gas emissions. Urgent action is needed to achieve carbon neutrality in the shipping industry for sustainability.
Enna Hirata, Kevin X. Li, Daisuke Watanabe   +2 more
doaj   +1 more source

Long‐Term Human Skin Platform for Modeling Chronic Inflammation, Environmental Stress, and Therapeutic Intervention

Advanced Science, EarlyView.
An advanced, long‐term human skin platform maintains native skin structure and key tissue functions for up to four weeks. The platform models chronic inflammation, aging‐related skin changes, and UVB damage, enabling drug and topical interventions—including anti‐inflammatory therapy, senolytic treatment, and sunscreen—to be evaluated in intact human ...
Purnendu Kumar Sharma, Evelien Schaafsma, Elysia Anderson, Jocelyn Chiari, Paige Thompson, Erin Galt, Sunghoon Lee, Jason Holsapple, Sai Hein, Bailey L. Coates, Jade Michaud, Sabrina Zuccaro, Lia Kent, Chris Hinojosa, Kyung‐Jin Jang   +14 more
wiley   +1 more source