Results 61 to 70 of about 276,492 (307)

Governing the Arctic: The Russian State Commission for Arctic Development and the Forging of a New Domestic Arctic Policy Agenda

open access: yesArctic Review on Law and Politics, 2019
After a period of relative neglect in the 1990s and early 2000s, the Arctic is back on the agenda of the Russian authorities. To ensure efficient coordination and implementation of its Arctic strategy, the government in 2015 established a State ...
Helge Blakkisrud
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Light Transmission Through Arctic Sea Ice - Large-Scale Studies on Seasonality and Spatial Variability [PDF]

open access: yes, 2013
Arctic sea ice has declined and become thinner and more seasonal during the last decade. One consequence of this is that the surface energy budget of the Arctic Ocean is changing.
Arndt, Stefanie   +2 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Sea ice trends in climate models only accurate in runs with biased global warming

open access: yes, 2017
Observations indicate that the Arctic sea ice cover is rapidly retreating while the Antarctic sea ice cover is steadily expanding. State-of-the-art climate models, by contrast, typically simulate a moderate decrease in both the Arctic and Antarctic sea ...
Eisenman, Ian, Rosenblum, Erica
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Visualizing population dynamics of alaska\u27s arctic communities [PDF]

open access: yes, 2009
Arctic demography has previously been reviewed on a large scale, across the circumpolar nations. We look instead at some recent population dynamics on sub-regional to community scales, focusing on Arctic Alaska.
Hamilton, Lawrence C., Mitiguy, Angela M
core   +1 more source

Arctic Port State Control as a Tool of Enforcement of the Polar Code

open access: yesКонтуры глобальных трансформаций: политика, экономика, право, 2019
Intensification of Arctic shipping requires the regional states to take appropriate measures aimed at mitigation of emerging risks. This relates to ensuring the compliance by vessels with the relevant provisions of international law in the field of ...
A. A. Todorov
doaj   +1 more source

Russia in the Arctic. Will the State Commission be its helmsman? [PDF]

open access: yesАрктика и Север, 2016
The article is focused on the analysis of the decisions on the development and exploration of the Arctic. It also reveals the activity of the State Commission on the Development of the Arctic. It notes the slow solution of problems of energy, information,
Valeriy P. Zhuravel
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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