Results 181 to 190 of about 287,804 (304)

Elevating the standards of hypofibrinogenemia in trauma: Higher thresholds of admission fibrinogen predict mortality and organ dysfunction

open access: yesTransfusion, EarlyView.
Abstract Background The precise thresholds at which admission fibrinogen predicts mortality and organ dysfunction in trauma patients are unknown. Study Design and Methods Retrospective study at a single trauma center. Inclusion criteria: 18–89 years, traumatic mechanism, transported from scene, and fibrinogen obtained within 30‐min of arrival ...
Justin Richards   +4 more
wiley   +1 more source

Retrospective Assessment of the Oxygenation Index in Dogs Undergoing Mechanical Ventilation for Primary Pulmonary Parenchymal Disease

open access: yesJournal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To assess the association between the oxygenation index (OI) and survival in mechanically ventilated dogs with primary pulmonary parenchymal disease. Design Retrospective, multicenter study. Setting Three veterinary medical teaching institutions and one private veterinary referral center.
Tereza Stastny   +7 more
wiley   +1 more source

ARDS Treatment Challenged [PDF]

open access: yesMilitary Medicine, 1999
D A, Amundson, K D, Gubler, J S, Parrish
openaire   +2 more sources

Role of RIPK1/RIPK3/MLKL signalling pathway in sepsis‐associated acute kidney injury

open access: yesExperimental Physiology, EarlyView.
Abstract Sepsis‐associated acute kidney injury (SA‐AKI) is a common clinical syndrome in critically ill patients, and its high mortality rate is closely related to complex pathological mechanisms. Existing studies have shown that the pathophysiological process of SA‐AKI involves complex multi‐mechanism interactions, including an uncontrolled systemic ...
Huijun Yin, Jingyi Wang, Huirong Han
wiley   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise   +2 more
wiley   +1 more source

Drafting the calmodulation playbook: Emerging structural insights into transient receptor potential channel regulation by calmodulin

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Calmodulin (CaM) is a ubiquitous calcium (Ca2+) sensor that translates intracellular Ca2+ signals into modulation of hundreds of effector proteins including ion channels. CaM is increasingly recognized as a key regulator of the transient receptor potential (TRP) channel family, yet the underlying ‘calmodulation playbook’ is only ...
Aden M. Alemayhu, Candice E. Paulsen
wiley   +1 more source

Alternative Lead ECG Placements

open access: yesAnnals of Noninvasive Electrocardiology, Volume 31, Issue 3, May 2026.
Alternative ECG lead placements can improve diagnostic yield when the standard 12‐lead ECG is suboptimal or infeasible. This review summarizes practical, scenario‐driven modifications (right‐sided, posterior, seated/prone, Lewis, Fontaine, torso‐based, and monitoring configurations) to better detect ischemia, right ventricular disease/ARVD, and ...
José Luis Morales‐Arteaga   +12 more
wiley   +1 more source

Remote Text‐Supplemented Audiobook Intervention Supports Children's Explicit and Incidental Vocabulary Learning

open access: yesDevelopmental Science, Volume 29, Issue 3, May 2026.
ABSTRACT Vocabulary knowledge is foundational to educational success, but significant gaps exist between students with reading disabilities or those from disadvantaged backgrounds and their peers. These gaps have cascading effects, as children with lower vocabulary knowledge are less likely to acquire new words through independent reading and are less ...
Halie A. Olson   +3 more
wiley   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

open access: yes
Transfusion, EarlyView.
Thane Kubik   +2 more
wiley   +1 more source

Acute Respiratory Distress Syndrome in Adult Patient With RSV Infection: A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT We described the case of a 54‐year‐old woman with no history of immunodeficiencies admitted to the ICU of our university hospital due to acute respiratory failure and ARDS secondary to severe community‐acquired pneumonia (sCAP) caused by RSV infection.
Gioacchina Martina Campione   +12 more
wiley   +1 more source

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