Results 41 to 50 of about 299,530 (310)

Simvastatin to reduce pulmonary dysfunction in patients with acute respiratory distress syndrome: the HARP-2 RCT

Efficacy and Mechanism Evaluation, 2018
Background: Acute lung injury is a common devastating clinical syndrome characterised by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure, and is a major cause of morbidity and mortality.
Daniel F McAuley, John G Laffey, Cecilia M O’Kane, Gavin D Perkins, Brian Mullan, Thomas J Trinder, Paul Johnston, Phillip A Hopkins, Andrew J Johnston, Lynn Murphy, Christine McNally, Ashley M Agus, Clíona McDowell, Colette Jackson   +13 more
doaj   +1 more source

COVID-19-related Secondary Bacterial Infections in Intubated Critical Illness

Cam & Sakura Medical Journal, 2023
Objective: The prevalence, occurrence, and characteristics of bacterial infection in individuals with severe acute respiratory syndrome coronavirus-2 is primarily unknown. In this research, we examined the effects of secondary bacterial infections (SBI),
Derya Tatlısuluoğlu, Gülçin Hilal Alay, Onur Özalp, Güldem Turan   +3 more
doaj   +1 more source

Effect of Rosuvastatin on Acute Kidney Injury in Sepsis-Associated Acute Respiratory Distress Syndrome. [PDF]

, 2018
Background:Acute kidney injury (AKI) commonly occurs in patients with sepsis and acute respiratory distress syndrome (ARDS). Objective:To investigate whether statin treatment is protective against AKI in sepsis-associated ARDS.
Hsu, Raymond K, Levitt, Joseph E, Liu, Kathleen D, Matthay, Michael A, Thompson, Boyd Taylor, Truwit, Jonathon D   +5 more
core   +3 more sources

Post-COVID-19 pulmonary fibrosis: A case series and review of literature

Journal of Family Medicine and Primary Care, 2021
The most common lung problem faced by a post-COVID patient is lung fibrosis. Clinical recovery is generally complete in mild-to-moderately severe COVID-19 cases but a small proportion of patients with severe disease may go on to develop lung fibrosis ...
Deependra K Rai, Subhash Kumar, Nishant Sahay   +2 more
doaj   +1 more source

Prolonged Glucocorticoid Treatment in ARDS: Impact on Intensive Care Unit-Acquired Weakness. [PDF]

, 2016
Systemic inflammation and duration of immobilization are strong independent risk factors for the development of intensive care unit-acquired weakness (ICUAW).
Hermans, Greet, Meduri, Gianfranco Umberto, Schwingshackl, Andreas   +2 more
core   +1 more source

Acute Respiratory Distress Syndrome (ARDS) Management Severe COVID-19

Indonesian Journal of Anesthesiology and Reanimation (IJAR), 2023
Introduction: The Coronavirus disease 2019 (COVID-19) caused a global pandemic and many management challenges. Acute Respiratory Distress Syndrome (ARDS) is one of the most common pneumonia complications in COVID-19 cases.
Helen Yudi Irianto, Akhmad Yun Jufan
doaj   +1 more source

Lung Microphysiological System Validates Novel Cell Therapy for Acute Respiratory Distress Syndrome

Advanced Biology, EarlyView.
This study aims to evaluate the efficacy of primed mesenchymal stem cells (pMSCs) as an alternative treatment for Acute Respiratory Distress Syndrome (ARDS), based on a novel lung microphysiological system (MPS) to test the efficacy of pMSCs over the standard treatment, Dexamethasone.
Bokyong Kim, So‐Hui Kim, Jieun Kim, Eun‐Young Eo, Hyung‐Jun Kim, Jae Ho Lee, Choon‐Taek Lee, Taeho Kong, Su Kyoung Seo, Seunghee Lee, Jeongbin Park, Young‐Jae Cho   +11 more
wiley   +1 more source

Predictive Value of the Baseline and Early Changes in Blood Eosinophils for Short-Term Mortality in Patients with Acute Respiratory Distress Syndrome

Journal of Inflammation Research, 2022
Junnan Peng,* Rui Tang,* Di Qi, Qian Yu, Hao Hu, Wen Tang, Jing He, Daoxin Wang Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China*These authors ...
Peng J, Tang R, Qi D, Yu Q, Hu H, Tang W, He J, Wang D   +7 more
doaj  

Noninvasive Ventilation of Patients with Acute Respiratory Distress Syndrome: Insights from the LUNG SAFE Study [PDF]

, 2017
RATIONALE: Noninvasive ventilation (NIV) is increasingly used in patients with acute respiratory distress syndrome (ARDS). The evidence supporting NIV use in patients with ARDS remains relatively sparse.
Antonelli, Massimo, Arabi, Yaseen M, Bauer, Philippe R, Bellani, Giacomo, Berghe, Caroline, Brochard, Laurent, Bulpa, Pierre, Bumbasirevic, Vesna, Dive, Alain-Michel, ESICM Trials Group, Esteban, Andres, Fan, Eddy, Gattinoni, Luciano, Laffey, John G, Larsson, Anders, LUNG SAFE Investigators, Madotto, Fabiana, McAuley, Daniel F, Pesenti, Antonio, Pham, Tài, Piquilloud, Lise, Ranieri, Marco, Rubenfeld, Gordon D, Slutsky, Arthur S, Thompson, B Taylor, van Haren, Frank, Wittebole, Xavier, Wrigge, Hermann   +27 more
core   +2 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source