Results 41 to 50 of about 76,862 (262)
This article presents a mapping method that seeks to provide urban planning with a diagnostic overview of the underground resources of an urban area. Resource potentials (for buildable space, groundwater or geomaterial extraction and geothermal energy ...
Michael R. Doyle
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Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
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Sustainable land management (SLM) is the use of land resources while preserving their production potential. Determining watershed characteristics is an important component of SLM, especially in areas with significant potential for land use change.
Turan Yüksek, Hurem Dutal
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We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
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Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Onomastic mentions about the first “protected areas” in the Romanian space
The article aims to highlight the distribution in the Romanian space of the first "protected areas", attested in the Middle Ages. These mentions are toponymic highlighted by names derived from the word, with Slavic origin Braniște, which meant the place ...
Ionel Boamfă
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Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
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The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
proof of the discreteness of the bosonic membrane spectrum
Using a spectral theorem for Schrodinger like equations, we present a proof of the discreteness of the spectrum for open bosonic membrane, considering L2 immersion maps from the 2 dimensional interval, at constant time, to at minkowski space.
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