Results 51 to 60 of about 76,862 (262)

Controlling chaos in area-preserving maps [PDF]

Physica D: Nonlinear Phenomena, 2005
We describe a method of control of chaos that occurs in area-preserving maps. This method is based on small modifications of the original map by addition of a small control term. We apply this control technique to the standard map and to the tokamap.
Chandre, Cristel, Vittot, Michel, Elskens, Yves, Ciraolo, Guido, Pettini, Marco   +4 more
openaire   +4 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Tracking site-scale tidal flat dynamics using time-series satellite data and Google Earth Engine over the past 40 years

Oceanological and Hydrobiological Studies
Tidal flats (TFs), the global hotspots of biodiversity and providers of coastal protection, are changing due to land reclamation, industrialization, and climate change.
Arif Maham, Xing Qianguo, Li Jie
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Chaotic and fractal maps in higher-order derivative dynamical systems

Frontiers in Physics
Hamiltonian maps are considered a class of dynamical systems that hold meticulous properties used to model a large number of complex dynamical systems.
Rami Ahmad El-Nabulsi, Rami Ahmad El-Nabulsi, Rami Ahmad El-Nabulsi, Waranont Anukool, Waranont Anukool, Waranont Anukool   +5 more
doaj   +1 more source

Socio-economic and land cover changes analysis in a landscape with agricultural matrix

Italian Journal of Agronomy, 2009
The research involved the application of CORINE Land Cover categories in order to analyse changes in land cover and in the socio-economic system over the last 50 years in Molise (Southern Italy).
Piera Di Marzio, Paolo Di Martino, Luigi Mastronardi, Paola Fortini, Carmen Giancola, Vincenzo Viscosi   +5 more
doaj   +1 more source

Area-Preserving Mappings for the Visualization of Medical Structures [PDF]

, 2003
In this note, we present a method for flattening anatomical surfaces such as branched vessels and intestinal tracts in an area-preserving way. This method is based on the theory of optimal mass transport and conformal mapping of surfaces. The flattened representations differ minimally from conformality in a certain precise sense. Potential applications
Lei Zhu 0001, Steven Haker, Allen R. Tannenbaum   +2 more
openaire   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source