Results 91 to 100 of about 3,286,995 (272)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Sophisticated software systems for small self-contained space shuttle payload G285 [PDF]

open access: yes
The increasing development of small microprocessor systems has allowed the use of more advanced software in the area of control systems. This paper discusses the development of software for small Space Shuttle Getaway Special Project payloads using ...
Burkhardt, Robert
core   +1 more source

Agile-SD: A Linux-based TCP Congestion Control Algorithm for Supporting High-speed and Short-distance Networks [PDF]

open access: yes, 2015
Recently, high-speed and short-distance networks are widely deployed and their necessity is rapidly increasing everyday. This type of networks is used in several network applications; such as Local Area Networks (LAN) and Data Center Networks (DCN).
Ali, Borhanuddin   +3 more
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Perfectly Aligned Shallow Ensemble Nitrogen-Vacancy Centers in (111) Diamond

open access: yes, 2017
We report the formation of perfectly aligned, high-density, shallow nitrogen vacancy (NV) centers on the ($111$) surface of a diamond. The study involved step-flow growth with a high flux of nitrogen during chemical vapor deposition (CVD) growth, which ...
Hatano, Mutsuko   +5 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Back to Basics: Meaning of the Parameters of Fractional Order PID Controllers

open access: yesMathematics, 2019
The beauty of the proportional-integral-derivative (PID) algorithm for feedback control is its simplicity and efficiency. Those are the main reasons why PID controller is the most common form of feedback.
Inés Tejado   +4 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

A proposition for machining error estimation based on geometric analysis of ball end milling

open access: yesNihon Kikai Gakkai ronbunshu, 2017
The ball end mill is used as a tool for cutting the metal mold and some complicated shape lake a screw. The demand for the precise machining of the ball end milling is increasing. The ball end milling has the unavoidable problem of machining error by the
Hisanobu TERAI   +3 more
doaj   +1 more source

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