Results 51 to 60 of about 3,327,498 (302)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Put on your poker face? Neural systems supporting the anticipation for expressive suppression and cognitive reappraisal [PDF]

open access: yes, 2012
It is a unique human ability to regulate negative thoughts and feelings. Two well-investigated emotion-regulation strategies (ERSs), cognitive reappraisal and expressive suppression, are associated with overlapping prefrontal neural correlates, but ...
De Raedt, Rudi   +2 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Ultrafast Codes for Multiple Adjacent Error Correction and Double Error Detection

open access: yesIEEE Access, 2019
Reliable computer systems employ error control codes (ECCs) to protect information from errors. For example, memories are frequently protected using single error correction-double error detection (SEC-DED) codes.
Luis-J. Saiz-Adalid   +4 more
doaj   +1 more source

A Reviewing Approach to Analyze the Advancements of Error Detection and Correction Codes in Channel Coding With Emphasis on LPWAN and IoT Systems

open access: yesIEEE Access, 2023
Error control coding improves reliability and efficiency of wireless communication systems. This research delves into the latest advancements in error control coding schemes for wireless communication systems, with a specific focus on their application ...
Muhammad Moazzam Ali   +5 more
doaj   +1 more source

Diagnosing multiplicative error by lensing magnification of type Ia supernovae

open access: yes, 2015
Weak lensing causes spatially coherent fluctuations in flux of type Ia supernovae (SNe Ia). This lensing magnification allows for weak lensing measurement independent of cosmic shear.
Zhang, Pengjie
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Multi-area load frequency cooperative control based on multi-agent deep reinforcement learning

open access: yes电力工程技术
With the integration of large-scale renewable energy, the frequency stability of power systems has been subjected to severe challenges. In this study, an expert-prefilled multi-agent twin delayed deep deterministic policy gradient (EP-MATD3) algorithm ...
Qingyu XU   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Directional Active Noise Control with a Local Minimax Error Criterion

open access: yesApplied Sciences, 2019
The traditional mean squared error (MSE) criterion can be formulated as a quadratic function of a vector of control filter coefficients, and it is easy to obtain optimal control filter coefficients. Although the MSE criterion can lead to noise reductions
Kexun Chi   +4 more
doaj   +1 more source

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