Results 81 to 90 of about 6,402,628 (197)
Development of Circumventricular Organs in the Mirror of Zebrafish Enhancer-Trap Transgenics
The circumventricular organs (CVOs) are small structures lining the cavities of brain ventricular system. They are associated with the semitransparent regions of the blood-brain barrier (BBB).
Marta García-Lecea +11 more
doaj +1 more source
Neurons in area postrema mediate vasopressin-induced enhancement of the baroreflex
Intravenous infusion of arginine vasopressin (AVP) has been shown to enhance baroreflex sensitivity, and this enhancement is dependent on the integrity of the area postrema.
V. S. Bishop, B. F. Cox, M. Hay
core +1 more source
Glial Endozepines Inhibit Feeding-Related Autonomic Functions by Acting at the Brainstem Level
Endozepines are endogenous ligands for the benzodiazepine receptors and also target a still unidentified GPCR. The endozepine octadecaneuropeptide (ODN), an endoproteolytic processing product of the diazepam-binding inhibitor (DBI) was recently shown to ...
Florent Guillebaud +11 more
doaj +1 more source
ABSTRACT Aims No studies have investigated the synergistic effectiveness of Glucagon‐Like Peptide 1 Receptor Agonists (GLP1RAs) in patients with persistent obesity following bariatric surgery. The GLP‐1 Receptor Agonists Post‐Bariatric Surgery (GRABS) Trial aims to investigate the effectiveness of tirzepatide (TRZ) versus standard of care (SOC) after ...
J. M. Samuels +12 more
wiley +1 more source
Opioid Modulation of Major Neurotransmitter Systems: Acute, Chronic, and Withdrawal Effects
Opioids are widely used but also frequently misused drugs that affect multiple neurotransmitter systems, including dopaminergic, glutamatergic, GABAergic, serotonergic, and cholinergic pathways. Opioid‐induced neuroadaptations depend on the duration of drug exposure, with distinct changes also emerging following drug discontinuation.
Daniela Novakova +2 more
wiley +1 more source
Area Postrema: A Unique Regulator of Cardiovascular Function
The area postrema, which does not have a blood-brain barrier, can sense changes in levels of blood-borne hormones. This circumventricular organ plays an important role in animal models of hypertension, recovery from hemorrhage, control of baroreflexes ...
KL Barnes +3 more
core +1 more source
ABSTRACT Background Recent 2025 neuromyelitis optica spectrum disorder (NMOSD) criteria distinguish AQP4‐IgG‐positive disease from seronegative‐syndromic groups, into which double‐seronegative‐NMOSD (DN‐NMOSD) may be reclassified, suggesting the need to better characterize DN‐NMOSD within prior diagnostic frameworks.
Jae‐Won Hyun +8 more
wiley +1 more source
GLP‐1 Receptor Agonists and Weight Loss: A Critical Review of Mechanisms
ABSTRACT GLP‐1 receptor agonist medications have the potential to promote marked weight loss, but maximal and sustained benefit may be compromised by poor compliance and cessation of use. Development of next‐generation medications that address current obstacles to effective use and development of effective adjunct treatments will benefit from better ...
Giorgia Rutigliani +8 more
wiley +1 more source
Chemotherapy‐induced nausea and vomiting (CINV) remains a significant clinical problem despite modern antiemetics. In particular, antiemetic strategies for emerging cancer therapies lack detailed evaluation. This randomized trial analyzed hourly CINV data for patients with early breast cancer who received either docetaxel plus cyclophosphamide (TC) or ...
Manuel Hörner +16 more
wiley +1 more source

