Results 81 to 90 of about 478,663 (300)

Receiver Operating Characteristic (ROC) curve and the Area Under the Curve (AUC) values for training and test data. [PDF]

, 2013
Receiver Operating Characteristic (ROC) curve and the Area Under the Curve (AUC) values for training and test data.
Mark H. Deakos (310138), Dean L. Urban (119763), David W. Johnston (310123), Joseph R. Mobley Jr (310140), Julian Tyne (310125), Robin W. Baird (159624), Adam A. Pack (310141), Susan H. Rickards (310134), Suzanne Yin (310130), Marie Chapla Hill (310142), Lars Bejder (310127), Lesley H. Thorne (310122)   +11 more
core   +1 more source

Dual therapeutic interventions to optimize vancomycin exposure and reduce nephrotoxicity: a cohort study from a single center

BMC Nephrology
Background Vancomycin-associated Acute Kidney Injury (AKI) is a significant global concern, increasing healthcare costs, morbidity, and mortality. This Quality Improvement Project (QIP) aimed to reduce supratherapeutic vancomycin concentrations and AKI ...
Janice Xuanhui Li, Horng-Ruey Chua, Gladys Wei-Teng Chung, Jyoti Somani, Yi Da   +4 more
doaj   +1 more source

Feasibility of vancomycin AUC24 monitoring using peak and trough concentrations in pediatric patients: a prospective multicenter study

Frontiers in Pharmacology
BackgroundVancomycin remains a key medication in treating infections in pediatric patients, particularly those caused by methicillin-resistant Staphylococcus aureus (MRSA).
Majed H. Nahari, Majed H. Nahari, Abdullah Alsultan, Renad A. Alshuraim, Abdullah Altuwayjiri, Sultan Alotaibi, Majed Aljeraisy, Majed Aljeraisy   +7 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Evaluation of everolimus pharmacokinetic monitoring based on trough concentration and area under the blood concentration time curve in kidney transplantation

BMC Nephrology
Background Everolimus (EVR) is widely used in kidney transplantation; however, the optimal sampling time point for therapeutic drug monitoring and the relationship between EVR exposure and adverse events under tacrolimus-based regimens remain unclear ...
Shota Fukae, Yoichi Kakuta, Soichi Matsumura, Ryo Tanaka, Masataka Kawamura, Shigeaki Nakazawa, Norio Nonomura   +6 more
doaj   +1 more source

A molecular computational model improves the preoperative diagnosis of thyroid nodules

BMC Cancer, 2012
Background Thyroid nodules with indeterminate cytological features on fine needle aspiration (FNA) cytology have a 20% risk of thyroid cancer. The aim of the current study was to determine the diagnostic utility of an 8-gene assay to distinguish benign ...
Tomei Sara, Marchetti Ivo, Zavaglia Katia, Lessi Francesca, Apollo Alessandro, Aretini Paolo, Di Coscio Giancarlo, Bevilacqua Generoso, Mazzanti Chiara   +8 more
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Distribution of the area under the curve (AUC) for various anthropometric measurements. [PDF]

, 2014
Distribution of the area under the curve (AUC) for various anthropometric measurements.
Easmon Otupiri (630129), Priscilla Wobil (630130), Michelle J. Hindin (309257), Samuel Blay Nguah (301503)   +3 more
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Area under the curve (AUC) of risk models in different AMD severity stages. [PDF]

, 2016
Area under the curve (AUC) of risk models in different AMD severity stages.
Tina Schick (627467), Eva Viehweger (2817700), Carel B. Hoyng (552359), Lebriz Altay (2817703), Sascha Fauser (144944), Moritz Felsch (2813953), Anneke I. den Hollander (142854)   +6 more
core   +1 more source