Results 51 to 60 of about 128,871,322 (303)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Area under the curve for Model C.

, 2023
Area under the curve for Model C.
Irazú Contreras-Yáñez (3149580), Ana Fresán Orellana (14419939), José R. Galindo-Donaire (14419936), Guillermo Guaracha-Basáñez (10047381), Virginia Pascual-Ramos (3149583), Gabriela Hernández-Molina (11105448), Oswaldo Briseño-González (14419942)   +6 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Receiver operating characteristic curve

Current Medicine Research and Practice, 2012
A receiver operating characteristic (ROC) curve is a plot of tradeoff between sensitivity and specificity. It is a plot that evaluates a diagnostic test for a continuous variable between diseased and non-diseased subjects.
Anita Singh, Vivek Choudhury, Satish Saluja   +2 more
doaj  

Assessment of pleural fluid adenosine deaminase and alkaline phosphatase in tubercular and non-tubercular effusions

Asian Journal of Medical Sciences, 2023
Background: Many studies have showed that adenosine deaminase (ADA) and alkaline phosphatase (ALP) values were highly supportive in the diagnosis of tuberculosis but comparison between ADA and ALP has not been much documented in pleural fluid (PF) in ...
Santanu Mondal , Swati Bhattacharyya , Subhra Mitra   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Association between body mass index and diabetes mellitus in tuberculosis patients in China: a community based cross-sectional study

BMC Public Health, 2017
Background We planned to determine the association of body mass index (BMI) with diabetes mellitus (DM) and impaired fasting glucose (IFG) in Chinese pulmonary tuberculosis (PTB) patients.
Jing Cai, Aiguo Ma, Qiuzhen Wang, Xiuxia Han, Shanliang Zhao, Yu Wang, Evert G. Schouten, Frans J. Kok   +7 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Area under the ROC curve.

, 2018
Area under the ROC curve.
Ying Ba (5883845), Jian-ling Du (3416783), Qian Xing (3416804), Hao Wang (39217)   +3 more
core   +1 more source