Results 51 to 60 of about 270,097 (301)
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Evaluating the use of recycled glass in Cuban concrete production
With the purpose of using recycled glass in concrete mixtures as a partial substitute for sand and cement in Cuba, researches are carried out. This article shows the result at a laboratory scale in substituting fine aggregate and cement with ground glass
Lianis de los Ángeles Columbié Lamorú +3 more
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
This issue of Arena Journal emerges from a day-long symposium held at the University of Melbourne in 2013 marking fifty years of publications by the Arena group.
Hinkson, John +2 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Renewable Energy Venture Capital Fund Program Evaluation Report
ARENA engaged UTS to conduct a mid-term evaluation of the Renewable Energy Venture Capital Fund (REVC). The evaluation was conducted by University of Technology Sydney who were commissioned by ARENA.
Nagrath, K +4 more
core
El objetivo del estudio fue evaluar la presencia de microplásticos en la playa de San Vicente para la comprensión del alcance de la contaminación plástica que existe actualmente en las playas.
Kenia Thais Zambrano Witong +3 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

