Results 71 to 80 of about 270,097 (301)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
HABITUS DAN ARENA DALAM NOVEL TAMAN API KARYA YONATHAN RAHARDJO
Lingua Franca: Jurnal Bahasa, Sastra, dan Pengajarannya, 2018 Karya sastra lahir dari latar belakang dan dorongan dasar manusia untuk mengungkapkan eksisitensi dirinya. Karya sastra lahir bukan dari ruang kosong melompong, tetapi dari sebuah interaksi dengan realitas kehidupan manusia.
Everhard Markiano Solissa
doaj
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
60 years of EU competition law: stocktaking and future prospects
, 2017 The purpose of this book, the fourth volume of the book series “I Quaderni del Corso di perfezionamento in diritto dell’Unione europea”, is to analyse some of the most recent developments in EU competition law and EU State aids law at their sixty-year ...
Mastroianni, Roberto +2 more
core
Libraries as Contestation Arena of the Stakeholders to Achieve Their Goals
Insaniyat: Journal of Islam and Humanities, 2019 The management of university libraries in Indonesia has been intervened from foreign institutions through a donation of library materials which seem for the benefit of the academic community, but it is for the benefit of the donors.
Luki Wijayanti
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Artists rendering of the proposed arena for Saint Louis University
, 2005 Artists rendering of the proposed arena for Saint Louis University.
Unknown creator; St. Louis University
core
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source