Results 21 to 30 of about 195,763 (259)
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
, 2019 Arge disparilis (Kirby, 1882). МатериаΛ: Бычиха, 18.07.2017 — 1♀ (ΑубатоΛов). Распространение: Хабаровский кр., Приморье; Корея, Япония. Примечание. Это первая нахоΔка Δанного виΔа в Хабаровском крае. Ранее в России он быΛ известен тоΛько с территории Приморья (СунΔуков, ЛеΛей 2012; Sundukov 2017).
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Revista Brasileira de História & Ciências Sociais, 2015 Os comandantes de Guardas Nacionais tiveram um papel importante na construção do Estado argentino a partir de meados do século XIX. Isso se deveu, entre outras coisas, à grande capacidade para neutralizar os ataques indígenas, ou pelo menos, reduzir as ...
Leonardo Canciani
doaj +2 more sources
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
MATEC Web of Conferences, 2017 Recently, the depletion of petroleum resources and the impact of exhaust emission caused by combustion towards environmental has been forced to all researchers to come out with an alternative ways to prevent this situation become worse.
Kamaruddin M. Hazeem +4 more
doaj +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
dynoGP: Deep Gaussian Processes for Dynamic System Identification
International Journal of Adaptive Control and Signal Processing, EarlyView.This work introduces a novel class of deep models for system identification, dynamical deep Gaussian processes, which combine the strengths of data‐driven methods, such as those based on neural network architectures, with the ability to output a probability distribution for uncertainty representation.
Alessio Benavoli +2 more
wiley +1 more source
Barreras y facilitadores en las trayectorias de mujeres con Cáncer de Mama usuarias de Hospitales Públicos [PDF]
Revista Argentina de Salud Pública, 2018 El cáncer de mama (CM) es el segundo más común en el mundo y el más frecuente entre las mujeres. La incidencia varía entre regiones. Además, el CM es la quinta causa de muerte por cáncer a nivel mundial, la más frecuente en las regiones menos ...
Silvina, Ramos +10 more
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