Results 41 to 50 of about 246,254 (250)
EnABLing Cathepsin-Driven Melanoma Metastasis
Molecular & Cellular Oncology, 2018 Metastatic melanoma remains incurable for many due to its aggressive nature. Secreted cathepsins promote metastasis by cleaving matrix and activating pro-invasive proteases.
Rakshamani Tripathi, Rina Plattner
doaj +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Forest plot of Pro/Pro versus Arg/Arg+ Pro/Arg for all studies.
, 2013 Forest plot of Pro/Pro versus Arg/Arg+ Pro/Arg for all studies.
Jun Ye (346649) +3 more
core +1 more source
dynoGP: Deep Gaussian Processes for Dynamic System Identification
International Journal of Adaptive Control and Signal Processing, EarlyView.This work introduces a novel class of deep models for system identification, dynamical deep Gaussian processes, which combine the strengths of data‐driven methods, such as those based on neural network architectures, with the ability to output a probability distribution for uncertainty representation.
Alessio Benavoli +3 more
wiley +1 more source
A Comparative Study of an Lpg- Spark Ignition Engine using Liquid Sequential Injection Technique
MATEC Web of Conferences, 2016 The development of liquid phase Liquefied Petroleum Gas (LPG) as an alternative fuel for the gasoline fuel is becoming popular in spark ignition engines. In this research, an experimental work was conducted on a1.6L 4-cylinder multi-port injection engine.
Tukiman Mohd Mustaqim +4 more
doaj +1 more source
Italian Journal of Animal Science, 2021 Little is known how L-arginine (Arg) affects the ovine intestinal epithelial cells (IOECs) redox status induced by hydrogen peroxide (H2O2). This study aimed to examine the impact of Arg on IOECs subjected to H2O2-induced oxidative damage, intestinal ...
Hao Zhang +7 more
doaj +1 more source
Forest plot of Pro/Arg versus Arg/Arg for all studies.
, 2013 Forest plot of Pro/Arg versus Arg/Arg for all studies.
Jun Ye (346649) +3 more
core +1 more source
Advanced Engineering Materials, EarlyView.We develop a data‐driven method to derive the mathematical expressions of the Flory–Huggins interaction parameter χ for the swelling behavior of temperature–responsive hydrogels. Starting from initial assumptions of χ, our workflow combines Bayesian optimization, Flory–Rehner theory, and symbolic regression to generate candidate χ expressions.
Yawen Wang +2 more
wiley +1 more source
, 2012 Cytological preparations probed for ARG immunolocalization via electron microscopy of L. amazonensis wild type (WT), ARG knockout (arg−), and the add-backs arg−/+ARG and arg−/+argΔSKL promastigotes.
Stephen M. Beverley (174720) +4 more
core +1 more source