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Tumoral and Systemic Immune Correlates of Response to Concurrent Pembrolizumab and Chemoradiotherapy in Patients with Resected High-Risk Head and Neck Squamous Cell Carcinoma. [PDF]

open access: yesClin Cancer Res
Vujanovic L   +24 more
europepmc   +1 more source

Disrupted Neutrophil and Myeloid Cell Homeostasis and Effector Dysfunction Drive Vasculopathy in Idiopathic Inflammatory Myopathies. [PDF]

open access: yesCells
Carrillo-Vázquez DA   +11 more
europepmc   +1 more source
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The human arginases and arginase deficiency

Journal of Inherited Metabolic Disease, 1998
AbstractArginase is the final enzyme in the urea cycle. Its deficiency is the least frequently described disorder of this cycle. It results primarily in elevated blood arginine, and less frequently in either persistent or acute elevations in blood ammonia.
R, Iyer   +5 more
openaire   +2 more sources

Arginase in Glomerulonephritis

Nephron Experimental Nephrology, 2000
Arginase metabolizes <i>L</i>-arginine to <i>L</i>-ornithine and urea. Two arginase isoforms, AI (liver arginase) and AII (ubiquitously expressed, functions unknown), have been identified. It is clear that arginases potentially have important roles in addition to urea generation for high concentrations are present at ...
S N, Waddington, V, Cattell
openaire   +2 more sources

Arginase deficiency

The Indian Journal of Pediatrics, 1997
Hyperargininemia due to arginase deficiency is a rare, inherited, urea cycle disorder. We report a case of arginase deficiency in a 5-year old boy presenting with mild hyperammonemia, hyperargininemia, and dibasic aminoaciduria.
R, Christopher   +2 more
openaire   +2 more sources

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