Results 151 to 160 of about 753,681 (356)
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray+2 more
wiley +1 more source
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto+2 more
wiley +1 more source
Differential sensitivity of basal and acetylcholine-induced activity of nitric oxide to blockade by asymmetric dimethylarginine (ADMA) in the rat aorta [PDF]
<b>Background and purpose</b>: Previous work has shown that NG-monomethyl-l-arginine (l-NMMA) paradoxically inhibits basal, but not ACh-stimulated activity of nitric oxide in rat aorta.
Archer+29 more
core +2 more sources
Chemical Biology of Protein Arginine Modifications in Epigenetic Regulation
Post-translational modifications (PTMs) of histone proteins are a hallmark of epigenetic regulation. They provide a mechanism to modulate chromatin structure and constitute the main features of the so-called “histone code”.1 The proposed function of this
J. Fuhrmann+2 more
semanticscholar +1 more source
The use of organ‐on‐a‐chip (OOC) microfluidic platforms is expanding in biomedical research. While this emerging technology is becoming increasingly accessible, the stability of long‐term functional cultures remains a critical challenge to address. This study presents a straightforward, one‐step method for the functionalization of polydimethylsiloxane ...
Mitzi Pérez‐Calixto+7 more
wiley +1 more source
This study investigated the effects of dietary arginine (Arg) supplementation, just during lactation, on sow and litter performance, plasma concentrations of metabolites and hormones, and milk yield and composition in multiparous sows.
Cui ZHU+6 more
doaj
Presence of pKa Perturbations Among Homeodomain Residues Facilitates DNA Binding [PDF]
Homeodomain containing proteins are a broad class of DNA binding proteins that are believed to primarily function as transcription factors. Electrostatics interactions have been demonstrated to be critical for the binding of the homeodomain to DNA. An examination of the electrostatic state of homeodomain residues involved in DNA phosphate binding has ...
arxiv
A micromethod for the determination of glycocyamine in biological fluids and tissue extracts [PDF]
In the two following communications (1, 2) evidence is presented that glycocyamine is a normal precursor of creatine in the animal body. These studies required a satisfactory micromethod for the determination of glycocyamine.
Borsook, Henry, Dubnoff, Jacob W.
core
Urinary felinine excretion in intact male cats is increased by dietary cystine [PDF]
Felinine is a branched-chain sulfur amino acid present in the urine of certain Felidae, including domestic cats. The objective of the present study was to determine if additional cystine and/or dietary N would increase felinine and N-acetylfelinine ...
Hendriks, W.H.+4 more
core +2 more sources
An improved method for the microdetermination of arginine by use of 8-hydroxyquinoline [PDF]
G. Ceriotti, L Spandrio
openalex +1 more source