Results 151 to 160 of about 784,368 (407)
Selection of Arginine-Rich Anti-Gold Antibodies Engineered for Plasmonic Colloid Self-Assembly [PDF]
arXiv, 2014 Antibodies are affinity proteins with a wide spectrum of applications in analytical and therapeutic biology. Proteins showing specific recognition for a chosen molecular target can be isolated and their encoding sequence identified in vitro from a large and diverse library by phage display selection. In this work, we show that this standard biochemical
arxiv
Molecular dynamics studies of interactions between Arg9(nona-arginine) and a DOPC/DOPG(4:1) membrane [PDF]
AIP Advances 10, 105103 (2020), 2020 It has been known that the uptake mechanisms of cell-penetrating peptides(CPPs) depend on the experimental conditions such as concentration of peptides, lipid composition, temperature, etc. In this study we investigate the temperature dependence of the penetration of Arg9s into a DOPC/DOPG(4:1) membrane using molecular dynamics(MD) simulations at two ...
arxiv
Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity
eLife, 2016 The mammalian target of rapamycin complex 1 (mTORC1) is the key signaling hub that regulates cellular protein homeostasis, growth, and proliferation in health and disease.
Bernadette Carroll +12 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray +2 more
wiley +1 more source
Pegylated arginine deiminase synergistically increases the cytotoxicity of gemcitabine in human pancreatic cancer. [PDF]
, 2014 BackgroundPancreatic ductal adenocarcinoma has proven to be one of the most chemo-resistant among all solid organ malignancies. Several mechanisms of resistance have been described, though few reports of strategies to overcome this chemo-resistance have ...
Bold, Richard J +3 more
core +2 more sources
Reasons underlying certain tendencies in the data on the frequency of codon usage [PDF]
arXiv, 2009 The tendencies described in this work were revealed in the course of examination of adenine and uracil distribution in the mRNA encoding sequence. The study also discusses the usage of codons occupied by the amino acid arginine in the table of the universal genetic code.
arxiv
Analysis and modeling of low frequency local field oscillations in a hippocampus circuit under osmotic challenge: the possible role of arginine vasopressin circuit for hippocampal function [PDF]
arXiv, 2020 Electrophysiological time series were taken simultaneously in two locations in the hippocampus of a rat brain previously described as receiving innervation from the osmosensitive vasopressinergic neurons of the hypothalamus. A hyperosmotic saline solution injection was administered during the time of the experiment.
arxiv
Arginine Demethylation of G3BP1 Promotes Stress Granule Assembly*
Journal of Biological Chemistry, 2016 Stress granules (SGs) are cytoplasmic condensates of stalled messenger ribonucleoprotein complexes (mRNPs) that form when eukaryotic cells encounter environmental stress.
W. Tsai +5 more
semanticscholar +1 more source
Salt‐Compact Albumin as a New Pure Protein‐based Biomaterials: From Design to In Vivo Studies
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.A new class of materials built entirely of native albumin protein is designed using a simple protocol based on salt‐assisted compaction, breaking with current crosslinking strategies. This green process leads, surprisingly, to water‐insoluble handable materials with high preservation of their native protein structures and Young's modulus close to that ...
Eya Aloui +19 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto +2 more
wiley +1 more source