Results 161 to 170 of about 784,368 (407)

THE USE OF ARGININE CONTAINING TOOTHPASTES IN DENTAL HARD TISSUES REMINERALIZATION

Romanian Journal of Oral Rehabilitation, 2017
The study aimed to compare the remineralization capacity of toothpastes containing arginine by surface morphology evaluation and calcium and phosphate ions concentration assessment in enamel and dentine.
Simona Stoleriu, Sorin Andrian, Galina Pancu, Irina Nica, Gianina Iovan   +4 more
doaj  

Continuum gating current models computed with consistent interactions [PDF]

arXiv, 2017
The action potential signal of nerve and muscle is produced by voltage sensitive channels that include a specialized device to sense voltage. Gating currents of the voltage sensor are now known to depend on the back-and-forth movements of positively charged arginines through the hydrophobic plug of a voltage sensor domain.
arxiv  

Arginine side chain interactions and the role of arginine as a gating charge carrier in voltage sensitive ion channels

Scientific Reports, 2016
Gating charges in voltage-sensing domains (VSD) of voltage-sensitive ion channels and enzymes are carried on arginine side chains rather than lysine. This arginine preference may result from the unique hydration properties of the side chain guanidinium ...
Craig T. Armstrong, P. Mason, John G. Anderson, C. Dempsey   +3 more
semanticscholar   +1 more source

Arginine Kinase Activates Arginine for Phosphorylation by Pyramidalization and Polarization

ACS Catalysis
Arginine phosphorylation plays numerous roles throughout biology. Arginine kinase (AK) catalyzes the delivery of an anionic phosphoryl group (PO3-) from ATP to a planar, trigonal nitrogen in a guanidinium cation. Density functional theory (DFT) calculations have yielded a model of the transition state (TS) for the AK-catalyzed reaction.
Fabio Falcioni, Robert W. Molt, Yi Jin, Jonathan P. Waltho, Sam Hay, Nigel G. J. Richards, G. Michael Blackburn   +6 more
openaire   +3 more sources

Fabrication of a Lipopolysaccharide‐Targeting Peptide‐Based Colloid for Alleviating Carbapenem‐Resistant Enterobacteriaceae‐Induced Cutaneous Infection

Advanced Healthcare Materials, EarlyView.
In this study, a novel cationic peptide, IW is designed and synthesized, with a tandem‐repeat sequence demonstrating potent activities against a broad spectrum of clinically relevant Carbapenem‐resistant Enterobacteriaceae in both the planktonic and biofilm states. IW is then formulated with P407 to form IW‐P407 colloids.
Ping Zeng, Xinyi Ding, Chenyu Liu, Sheng Chen, Kin‐Fai Chan, Sharon Shui Yee Leung   +5 more
wiley   +1 more source

Arginine Metabolism in Bacterial Pathogenesis and Cancer Therapy

International Journal of Molecular Sciences, 2016
Antibacterial resistance to infectious diseases is a significant global concern for health care organizations; along with aging populations and increasing cancer rates, it represents a great burden for government healthcare systems.
L. Xiong, J. L. Teng, M. Botelho, R. C. Lo, S. Lau, P. Woo   +5 more
semanticscholar   +1 more source

Functional Biomaterials Derived from Protein Liquid–Liquid Phase Separation and Liquid‐to‐Solid Transition

Advanced Materials, EarlyView.
Protein can undergo liquid–liquid phase separation and liquid‐to‐solid transition to form liquid condensates and solid aggregates. These phase transitions can be influenced by post‐translational modifications, mutations, and various environmental factors.
Tianchen Li, Dea Ilhamsyah, Benedict Tai, Yi Shen   +3 more
wiley   +1 more source

Is NO the Answer? The Nitric Oxide Pathway Can Support Bone Morphogenetic Protein 2 Mediated Signaling [PDF]

, 2019
The growth factor bone morphogenetic protein 2 (BMP2) plays an important role in bone development and repair. Despite the positive effects of BMP2 in fracture healing, its use is associated with negative side effects and poor cost effectiveness, partly ...
Bormann, Nicole, Differ, Christopher, Klatte-Schulz, Franka, Knaus, Petra, Minkwitz, Susann, Wildemann, Britt   +5 more
core   +1 more source

Chemical Biology of Protein Arginine Modifications in Epigenetic Regulation

Chemical Reviews, 2015
Post-translational modifications (PTMs) of histone proteins are a hallmark of epigenetic regulation. They provide a mechanism to modulate chromatin structure and constitute the main features of the so-called “histone code”.1 The proposed function of this
J. Fuhrmann, Kathleen W. Clancy, P. Thompson   +2 more
semanticscholar   +1 more source

Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction

Advanced Materials, EarlyView.
We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin, Kendal P. Carrow, Alexander Chen, Madeline P. Hopps, JoJo J. Holm, Quincy P. Lyons, Michael B. Nguyen, Jervaughn D. Hunter, Assa Magassa, Elyse G. Wong, Kate Reimold, Sriya N. Paleti, Emily Gardner, Matthew P. Thompson, Colin G. Luo, Xiaoyu Zhang, Karen L. Christman, Nathan C. Gianneschi   +17 more
wiley   +1 more source