Results 161 to 170 of about 753,681 (356)

Enhancing Form Stability: Shrink‐Resistant Hydrogels Made of Interpenetrating Networks of Recombinant Spider Silk and Collagen‐I

Advanced Healthcare Materials, EarlyView.
A shrinkage‐resistant hydrogel is developed to confer post‐fabrication shape fidelity. The hydrogel, based on recombinant spider silk protein eADF4(C16)‐RGD and collagen‐I, exhibits tunable mechanical properties and shrink‐resistance in the presence of fibroblasts as well as muscle cells.
Xuen J. Ng, Tilman U. Esser, Vanessa T. Trossmann, Christoph Rudisch, Maren Fiedler, Kaveh Roshanbinfar, Zan Lamberger, Philipp Stahlhut, Gregor Lang, Thomas Scheibel, Felix B. Engel   +10 more
wiley   +1 more source

Synthesis of an arginine mimic for an antifungal octapeptide library : this thesis is presented in partial fulfilment of the requirements for the degree of Master of Science in Chemistry at Massey University, Palmerston North, New Zealand [PDF]

, 2008
A family of bioactive antifungal octapeptides has been established¹⁻³. The template for this library is based on peptides composed of two predefined amino acids, three arginines, and three unknown components. The arginine contains a guanidino group (pKa =
Sun, Hao
core  

Arginine Metabolism in Bacterial Pathogenesis and Cancer Therapy

International Journal of Molecular Sciences, 2016
Antibacterial resistance to infectious diseases is a significant global concern for health care organizations; along with aging populations and increasing cancer rates, it represents a great burden for government healthcare systems.
L. Xiong, J. L. Teng, M. Botelho, R. C. Lo, S. Lau, P. Woo   +5 more
semanticscholar   +1 more source

Advanced Materials for Biological Field‐Effect Transistors (Bio‐FETs) in Precision Healthcare and Biosensing

Advanced Healthcare Materials, EarlyView.
This review explores how advanced materials enhance Bio‐FETs for precision healthcare and biosensing. It covers their working principles, surface functionalization, and ultra‐sensitive detection capabilities. The integration of flexible designs, AI, and IoT for real‐time monitoring is discussed, along with challenges like material reproducibility and ...
Minal Pandey, Manish Bhaiyya, Prakash Rewatkar, Jitendra B. Zalke, Nitin P. Narkhede, Hossam Haick   +5 more
wiley   +1 more source

Concanavalin A-Binding Enzymes of Crotalus scutulatus scutulatus Venom [PDF]

, 1985
Crotalus scutulatus scutulatus crude venom was separated into two fractions by Concanavalin A Sepharose 4B affinity chromatography. The proteins binding to Con A exhibited phosphomonoesterase (orthophosphoric monoester phosphohydrolase EC 3.1.3.2 ...
Childs, C. K., Hinson, Michael W., Johnson, Bob D., Sifford, Dewey H.   +3 more
core   +4 more sources

Functional Biomaterials Derived from Protein Liquid–Liquid Phase Separation and Liquid‐to‐Solid Transition

Advanced Materials, EarlyView.
Protein can undergo liquid–liquid phase separation and liquid‐to‐solid transition to form liquid condensates and solid aggregates. These phase transitions can be influenced by post‐translational modifications, mutations, and various environmental factors.
Tianchen Li, Dea Ilhamsyah, Benedict Tai, Yi Shen   +3 more
wiley   +1 more source

Impact of Co-Excipient Selection on Hydrophobic Polymer Folding: Insights for Optimal Formulation Design [PDF]

arXiv
The stabilization of liquid biological products is a complex task that depends on the chemical composition of both the active ingredient and any excipients in solution. Frequently, a large number of unique excipients are required to stabilize biologics, though it is not well-known how these excipients interact with one another. To probe these excipient-
arxiv  

Porous Silicon Nanoneedles Efficiently Deliver Adenine Base Editor to Correct a Recurrent Pathogenic COL7A1 Variant in Recessive Dystrophic Epidermolysis Bullosa

Advanced Materials, EarlyView.
Base editing using nanoneedles efficiently corrects pathogenic variants in the type VII collagen gene of primary fibroblasts from patients with recessive dystrophic epidermolysis bullosa. Nanoneedle editing induces minimal and reversible transcriptional perturbations while restoring the production and secretion of functional type VII collagen.
Salman Ahmad Mustfa, Marija Dimitrievska, Cong Wang, Chenlei Gu, Ningjia Sun, Katarzyna Romańczuk, Pawel Karpinski, Łukasz Łaczmański, John A. McGrath, Joanna Jacków‐Malinowska, Ciro Chiappini   +10 more
wiley   +1 more source

Molecular basis and current strategies of therapeutic arginine depletion for cancer

International Journal of Cancer, 2016
Renewed interest in the use of therapeutic enzymes combined with an improved knowledge of cancer cell metabolism, has led to the translation of several arginine depletion strategies into early phase clinical trials.
Livingstone Fultang, A. Vardon, Carmela De Santo, F. Mussai   +3 more
semanticscholar   +1 more source

A Multifunctional Binder for Current‐Collector‐Free Zn Powder Anodes

Advanced Materials, EarlyView.
By introducing abundant polar groups as Zn2+ absorption sites and hydrogen bond arrays, a protein structure‐derived binder for ZP anode and iodine cathode is proposed. This design can regulate the Zn2+ flux, benefit the formation of free‐standing electrode, inhibit the side reactions, suppress the shuttle effect of polyiodides, and enable the large ...
Yanbo Wang, Xintao Ma, Xinru Yang, Rong Zhang, Hu Hong, Shixun Wang, Qing Li, Ze Chen, Zhaodong Huang, Haiming Lv, Chunyi Zhi   +10 more
wiley   +1 more source