Results 201 to 210 of about 753,681 (356)
Advanced Science, EarlyView.This study uses gut microbiome data to predict corticosteroid response in patients with immune thrombocytopenia (ITP). Fecal samples from 212 patients with ITP are sequenced. Six machine‐learning algorithms are used to train predictive models. The support vector machine‐based model integrated clinical data and selected microbial species, diversities ...
Feng‐Qi Liu +38 more
wiley +1 more source
Aquaculture, Fish and Fisheries, Volume 2, Issue 6, Page 540-551, December 2022., 2022 Abstract Feed effectors have been suggested to improve the efficiency of plant‐based shrimp diets by increasing attractability and palatability. This research trial aimed to expand upon previous Pacific white shrimp (Litopenaeus vannamei) research involving plant‐based diets, feed effectors and passive acoustic monitoring (PAM) in a laboratory setting ...
Samuel Walsh +4 more
wiley +1 more source
Growth inhibition of neurospora by canavanine, and its reversal [PDF]
, 1948 Canavanine, an amino acid from jack beans, was discovered by Kitagawa and coworkers in 1929 (1, 2). The substance is not combined in the proteins of the seed, but occurs in the free state, and makes up 2.5 per cent of the dry weight of jack beans (3). In
Horowitz, N. H., Srb, Adrian M.
core
CANAVANINE AND HOMOARGININE AS ANTIMETABOLITES OF ARGININE AND LYSINE IN YEAST AND ALGAE
, 1955 James B. Walker
openalex +1 more source
RFWD3 Reprograms Nucleotide Metabolism Through PHGDH to Induce Chemoresistance In Osteosarcoma
Advanced Science, EarlyView.RFWD3 is identified as a key regulator of cisplatin (DDP) sensitivity in osteosarcoma using a genome‐wide CRISPR screen. RFWD3 promotes PHGDH ubiquitination, enhancing NAD+‐mediated nucleotide biosynthesis. Knocking out RFWD3 sensitized osteosarcoma cells to DDP.
Wenchao Zhang +6 more
wiley +1 more source
, 2017 Understanding how different classes of molecules move across biological membranes is a prerequisite to predicting a solute's permeation rate, which is a critical factor in the fields of drug design and pharmacology.
Maibaum, Lutz, Pokhrel, Nihit
core +2 more sources
THE RÔLE OF GLUTAMINE IN THE SYNTHESIS OF ARGININE BY LACTOBACILLUS ARABINOSUS
, 1954 Robert L. Ory +2 more
openalex +1 more source
Advanced Science, EarlyView.This study reveals the tumor‐suppressive role of TRIM38 in colorectal cancer (CRC). TRIM38 is downregulated through DNA hypermethylation and correlates with unfavorable clinical features and poor prognosis. Mechanistically, TRIM38 inhibits CRC progression by promoting K48‐linked ubiquitination of CCT6A, leading to the destabilization of c‐Myc.
Yue Zhang +10 more
wiley +1 more source
THE DEGRADATION OF ARGININE BY CLOSTRIDIUM PERFRINGENS (BP6K)
, 1952 G Schmidt, Milan A. Logan, A. A. Tytell
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Advanced Science, EarlyView.This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran +7 more
wiley +1 more source