Results 201 to 210 of about 679,914 (276)

Enteral and intravenous supplementation of arginine and citrulline fail to prevent necrotizing enterocolitis in preterm neonatal pigs. [PDF]

JPEN J Parenter Enteral Nutr
Vonderohe C, Garcia Mancebo J, Melendez Hebib V, Stoll B, Didelija I, Elefson S, Mohammad M, Earls B, Guthrie G, Burrin D.   +9 more
europepmc   +1 more source

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source

Arginine amino acid, nano particles of zinc oxide, and stock density: Effect on growth performance, intestinal morphology, blood indices, and meat quality in broiler chickens. [PDF]

Poult Sci
Bahrampour K, Afzali N, Hosseini-Vashan SJ.   +2 more
europepmc   +1 more source

Acetylation Regulates ACSL4 Degradation Through Chaperone‐Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu, Zhichen Jiang, Chenglong Hong, Shu Yang, Shuqing Jin, Chenyu Wu, Kaijie Guo, Jiang Liu, Shaobo Xu, Chenggui Wang, Xiangyang Wang   +10 more
wiley   +1 more source

Enhanced gait following NW-RSA training links to reduced myostatin and improved L-arginine metabolites in older women with preserved vitamin D. [PDF]

Sci Rep
Skrobot W, Ziemann E, Jaworska J, Rodziewicz-Flis E, Micielska K, Ratajczak J, Orlikowska A, Lombardi G, Borkowska A, Kortas JA.   +9 more
europepmc   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

The Beneficial Effects of Guanidinoacetic Acid as a Functional Feed Additive: A Possible Approach for Poultry Production. [PDF]

Vet Sci
Elnesr SS, Shehab-El-Deen M.
europepmc   +1 more source

Stepwise Regulation of Cellular Oxidative Stress via Conductive‐Piezoelectric Integrated Microstructured Conduits for Enhanced Nerve Regeneration

Advanced Science, EarlyView.
This study presents a conductive‐piezoelectric integrated microstructured conduit for peripheral nerve regeneration. The conduit combines reduced graphene oxide with a piezoelectric nanofiber membrane, enhancing nerve repair through physical guidance, oxidative stress inhibition, and ultrasound‐activated electrical stimulation.
Dong Zhou, Mengxuan Bian, Lingyu Wei, Binghuang Yao, Qi Chen, Lan Xiao, Jing He, Jian Zhang, Yulin Li, Libo Jiang   +9 more
wiley   +1 more source

Arginine modulates the pH, microbial composition, and matrix architecture of biofilms from caries-active patients. [PDF]

Int J Oral Sci
Del Rey YC, Rikvold PD, Lund MB, Raittio EJ, Schramm A, Meyer RL, Schlafer S.   +6 more
europepmc   +1 more source

Engineering Compact Base Editors by AlphaFold‐Guided Mutation Scan and Escherichia coli‐Based Tri‐Selection

Advanced Science, EarlyView.
A miniaturized deaminase SsdAtox was scanned with AlphaFold to identify DNA binding pocket hot spots. Site‐saturation mutagenesis at gatekeeper residue K31 yielded ten‐fold activity enhancement. Trinity Screen, an E. coli‐based three‐in‐one platform selecting for high activity and reduced double‐strand breaks, enabled combinatorial evolution at DNA ...
Ryeo Gang Son, Goeun Kim, Jungjoon K. Lee   +2 more
wiley   +1 more source