Results 81 to 90 of about 844,163 (322)

Serum methylarginines and spirometry-measured lung function in older adults [PDF]

, 2013
Rationale: Methylarginines are endogenous nitric oxide synthase inhibitors that have been implicated in animal models of lung disease but have not previously been examined for their association with spirometric measures of lung function in humans ...
A Koarai, A Lara, A Wanner, AA Mangoni, AJ Cardounel, Angelo Zinellu, Arduino A. Mangoni, AS Buist, B Caplin, C Brindicci, C Gore, Ciriaco Carru, D Fliser, D Hole, E Schroeder, EB Schroeder, FLM Ricciardolo, FLM Ricciardolo, FP Nijkamp, G Segarra, GB Segarra, H Grasemann, JA Scott, JC Kips, JK Ward, John R. Attia, Kingsley Agho, M McEvoy, M Tulic, Manlio Vinciguerra, Mark A. McEvoy, MG Persson, ML Selley, MS Tockman, MT Bedford, P Bulau, Peter W. Schofield, PJ Barnes, PW Shaul, R Robbins, R Ten Broeke, Roseanne Peel, Roy L. Soiza, S Pullamsetti, SM Wells, Stephen J. Hancock, T Ahmad, Wayne T. Smith   +47 more
core   +8 more sources

Consequences of arginine and methionine supplementation on growth performance, intestinal health, and immune response in broiler chickens under concurrent heat stress and coccidia challenge

Poultry Science
We investigated the effects of arginine and methionine supplementation in reduced protein diets on performance of broilers under concurrent heat stress (HS) and coccidia challenge.
Guanchen Liu, Doyun Goo, Jihwan Lee, Adeleye M. Ajao, Revathi Shanmugasundaram, Elizabeth Ball, Yves Mercier, Todd J. Applegate, Ramesh Selvaraj, Ilias Kyriazakis, Oluyinka A. Olukosi, Woo K. Kim   +11 more
doaj   +1 more source

Refolding Technology for scFv Using a New Detergent, N-Lauroyl-L-glutamate and Arginine

Antibodies, 2012
Monoclonal antibodies to the soluble antigens or cell surface markers hold great promise as effective human therapeutics. One of the major disadvantages is its large size, which prevents efficient penetration into the target tissues.
Tsutomu Arakawa, Yoshiko Kita, Daisuke Ejima   +2 more
doaj   +1 more source

PLLA Composites Combined with Delivery System of Bioactive Agents for Anti-Inflammation and Re-Endothelialization

Pharmaceutics, 2022
The development of a biodegradable vascular scaffold (BVS) for the treatment of cardiovascular diseases (CVDs) still requires some improvement. Among them, re-endothelialization and anti-inflammation are clinically important to restore vascular function.
Seung-Woon Baek, Da-Seul Kim, Duck Hyun Song, Semi Lee, Jun-Kyu Lee, So-Yeon Park, Jun Hyuk Kim, Tae-Hyung Kim, Chun Gwon Park, Dong Keun Han   +9 more
doaj   +1 more source

Autophagy maintains tumor growth through circulating arginine

Nature, 2018
Autophagy captures intracellular components and delivers them to lysosomes, where they are degraded and recycled to sustain metabolism and to enable survival during starvation1–5.
Laura Poillet-Perez, Xiaoqi Xie, L. Zhan, Yang Yang, Daniel W. Sharp, Z. Hu, Xiaoyang Su, Anurag Maganti, Cherry Jiang, Wenyun Lu, Haiyan Zheng, M. Bosenberg, J. Mehnert, J. Y. Guo, Edmund Lattime, Joshua D. Rabinowitz, E. White   +16 more
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Nutrition et santé : lipides et protéines d’origine végétale - De nouvelles données pour juger de la qualité des protéines végétales chez l’homme - Implications et perspectives

Oléagineux, Corps gras, Lipides, 2003
La qualité des protéines pour l’alimentation de l’homme est un sujet très ancien mais les différentes méthodes proposées jusqu’ici pour évaluer la qualité protéique ont été largement critiquées, pour des problèmes conceptuels et méthodologiques.
Mariotti François, Tomé Daniel
doaj   +1 more source

Arginine and Immunity [PDF]

The Journal of Nutrition, 2007
For many years, dietary arginine supplementation, often combined with other substances, has been used as a mechanism to boost the immune system. Considerable controversy, however, exists as to the benefits and indications of dietary arginine due in part to a poor understanding of the role played by this amino acid in maintaining immune function ...
Petar J, Popovic, Herbert J, Zeh, Juan B, Ochoa   +2 more
openaire   +2 more sources

Is NO the Answer? The Nitric Oxide Pathway Can Support Bone Morphogenetic Protein 2 Mediated Signaling [PDF]

, 2019
The growth factor bone morphogenetic protein 2 (BMP2) plays an important role in bone development and repair. Despite the positive effects of BMP2 in fracture healing, its use is associated with negative side effects and poor cost effectiveness, partly ...
Bormann, Nicole, Differ, Christopher, Klatte-Schulz, Franka, Knaus, Petra, Minkwitz, Susann, Wildemann, Britt   +5 more
core   +1 more source