Results 111 to 120 of about 39,147 (291)

Selection of Arginine-Rich Anti-Gold Antibodies Engineered for Plasmonic Colloid Self-Assembly [PDF]

arXiv, 2014
Antibodies are affinity proteins with a wide spectrum of applications in analytical and therapeutic biology. Proteins showing specific recognition for a chosen molecular target can be isolated and their encoding sequence identified in vitro from a large and diverse library by phage display selection. In this work, we show that this standard biochemical
arxiv  

The paraventricular nucleus of the hypothalamus: a key node in the control of behavioural states

The Journal of Physiology, EarlyView.
Abstract figure legend The paraventricular nucleus (PVN) of the hypothalamus contains many different populations of neurons. Together, these neurons control numerous physiological functions and homeostatic behaviours. Created in BioRender. Iremonger, K.
Karl J. Iremonger, Emmet M. Power
wiley   +1 more source

Therapeutic Potential of Vasopressin-Receptor Antagonists in Heart Failure

Journal of Pharmacological Sciences, 2014
.: Arginine vasopressin (AVP) is a 9-amino acid peptide that is secreted from the posterior pituitary in response to high plasma osmolality and hypotension.
Yasukatsu Izumi, Katsuyuki Miura, Hiroshi Iwao   +2 more
doaj  

Reasons underlying certain tendencies in the data on the frequency of codon usage [PDF]

arXiv, 2009
The tendencies described in this work were revealed in the course of examination of adenine and uracil distribution in the mRNA encoding sequence. The study also discusses the usage of codons occupied by the amino acid arginine in the table of the universal genetic code.
arxiv  

Personalized Metabolic Analysis of Diseases [PDF]

arXiv, 2020
The metabolic wiring of patient cells is altered drastically in many diseases, including cancer. Understanding the nature of such changes may pave the way for new therapeutic opportunities, as well as the development of personalized treatment strategies for patients.
arxiv  

Essential Role of the Anterior Piriform Cortex in Mediating Social Novelty Output via a Top–Down Circuit

Advanced Science, Volume 12, Issue 13, April 3, 2025.
The anterior piriform cortex (APC) exhibits distinct neural firings and calcium transients in response to familiar and novel mice, with a more robust response to the novel one. Selectively inhibiting APC pyramidal neurons disrupt social novelty recognition without impairing basic odor discrimination.
Jingwei Zhou, Zhaoyang Yin, Zhiyun Chen, Hanyu Fu, Qun Li, Shan Li, Ying Zhang, Xianzhi Zhang, Dewei Tang, Anan Li, Dejuan Wang   +10 more
wiley   +1 more source

Association of Anaesthetists guidelines: the use of blood components and their alternatives

Anaesthesia, Volume 80, Issue 4, Page 425-447, April 2025.
Summary Background The administration of blood components and their alternatives can be lifesaving. Anaemia, bleeding and transfusion are all associated with poor peri‐operative outcomes. Considerable changes in the approaches to optimal use of blood components and their alternatives, driven by the findings of large randomised controlled trials and ...
Akshay Shah, Andrew A. Klein, Seema Agarwal, Andrew Lindley, Aamer Ahmed, Kerry Dowling, Emma Jackson, Sumit Das, Divya Raviraj, Rachel Collis, Anna Sharrock, Simon J. Stanworth, Paul Moor   +12 more
wiley   +1 more source

Molecular dynamics studies of interactions between Arg9(nona-arginine) and a DOPC/DOPG(4:1) membrane [PDF]

AIP Advances 10, 105103 (2020), 2020
It has been known that the uptake mechanisms of cell-penetrating peptides(CPPs) depend on the experimental conditions such as concentration of peptides, lipid composition, temperature, etc. In this study we investigate the temperature dependence of the penetration of Arg9s into a DOPC/DOPG(4:1) membrane using molecular dynamics(MD) simulations at two ...
arxiv  

Nausea: Current knowledge of mechanisms, measurement and clinical impact [PDF]

, 2015
Nausea is a subjective sensation, which often acts as a signal that emesis is imminent. It is a widespread problem that occurs as a clinical sign of disease or as an adverse effect of a drug therapy or surgical procedure.
Aapro, Alphin, Andrews, Andrews, Andrews, André, Beleslin, Chelen, Chen, Cluny, Coil, Conder, Cross-Mellor, Cubeddu, Cubeddu, Cubeddu, Cubeddu, Cullen, Davidson, de la Puente-Redondo, Diemunsch, Doweck, Elwood, Fan, Foss, Fredrikson, Fredrikson, Gralla, Hahn, Hannah Kenward, Hay Kraus, Hickman, Hikasa, Holmes, Horn, Horn, Hornby, Hu, Japundzic-Zigon, Jenns, Jonathan Elliott, Karine Savary-Bataille, Kenward, Kim, Koch, Koch, Koivuranta, Kowalski, Krawiec, Kretzing, Kretzing, Kristal, Kvale, Lacasse, Le Bars, Leeser, Limebeer, Limebeer, Limebeer, Limebeer, Limebeer, Limebeer, Lucot, Ludovic Pelligand, Mantione, Mayer, Medleau, Melzack, Miller, Minami, Minami, Morrow, Morrow, Morrow, Muth, Napadow, Otto, Parker, Parker, Parker, Parker, Poli-Bigelli, Quimby, Rau, Ritter, Rock, Roila, Rossmeisl, Rowe, Sanger, Sanger, Schwartz, Sedlacek, Shelke, Soderpalm, Stern, Tatewaki, Tramer, Vaha-Vahe, Villablanca, Watson, Yamakuni, Yamamoto, Yap, Yu   +104 more
core   +1 more source

Chronic stress induces behavioural changes through increased kynurenic acid by downregulation of kynurenine‐3‐monooxygenase with microglial decline

British Journal of Pharmacology, Volume 182, Issue 7, Page 1466-1486, April 2025.
Background and Purpose Alterations in tryptophan‐kynurenine (TRP‐KYN) pathway are implicated in major depressive disorder (MDD). α7 nicotinic acetylcholine (α7nACh) receptor regulates the hypothalamic–pituitary–adrenal (HPA) axis. We have shown that deficiency of kynurenine 3‐monooxygenase (KMO) induces depression‐like behaviour via kynurenic acid ...
Masaya Hasegawa, Kazuo Kunisawa, Bolati Wulaer, Hisayoshi Kubota, Hitomi Kurahashi, Takatoshi Sakata, Honomi Ando, Suwako Fujigaki, Hidetsugu Fujigaki, Yasuko Yamamoto, Taku Nagai, Kuniaki Saito, Toshitaka Nabeshima, Akihiro Mouri   +13 more
wiley   +1 more source