Impact of Co-Excipient Selection on Hydrophobic Polymer Folding: Insights for Optimal Formulation Design [PDF]
arXivThe stabilization of liquid biological products is a complex task that depends on the chemical composition of both the active ingredient and any excipients in solution. Frequently, a large number of unique excipients are required to stabilize biologics, though it is not well-known how these excipients interact with one another. To probe these excipient-
arxiv
Presence of pKa Perturbations Among Homeodomain Residues Facilitates DNA Binding [PDF]
arXiv, 2009 Homeodomain containing proteins are a broad class of DNA binding proteins that are believed to primarily function as transcription factors. Electrostatics interactions have been demonstrated to be critical for the binding of the homeodomain to DNA. An examination of the electrostatic state of homeodomain residues involved in DNA phosphate binding has ...
arxiv
Effect of angiotensin-converting enzyme inhibitor (SQ 20881) on the plasma concentration of angiotensin I, angiotensin II, and arginine vasopressin in the dog during hemorrhagic shock. [PDF]
, 1977 J.J. Morton +6 more
openalex +1 more source
Journal of Pharmacological Sciences, 2009 The neurohypophyseal peptide [Arg8]-vasopressin (AVP) is involved in diverse functions such as the regulation of body fluid homeostasis, metabolism, and hormone secretion.
Akito Tanoue
doaj
54: Arginine-Vasopressin (AVP) secretion and placental transfer in maternal (M) and foetal (F) sheep [PDF]
, 1976 P Czernichow +4 more
openalex +1 more source
AACE Clinical Case Reports, 2018 : Objective: Titration of desmopressin can be challenging during complex, lengthy surgical procedures in patients with chronic central diabetes insipidus (DI). Arginine vasopressin (AVP) may be the preferred treatment modality in these settings.
Khawla F. Ali, MD +7 more
doaj
Hyponatremia in the 2009 161-km Western States Endurance Run
, 2012 Purpose:To determine the incidence of exercise-associated hyponatremia (EAH), the associated biochemical measurements and risk factors for EAH, and whether there is an association between postrace blood sodium concentration ([Na+]) and changes in body ...
Hew-Butler, Tamara +4 more
core +1 more source
Nephrogenic Syndrome of Inappropriate Antidiuresis
International Journal of Pediatrics, 2012 Mutations in the vasopressin V2 receptor gene are responsible for two human tubular disorders: X-linked congenital nephrogenic diabetes insipidus, due to a loss of function of the mutant V2 receptor, and the nephrogenic syndrome of inappropriate ...
D. Morin +3 more
doaj +1 more source
Role of arginine vasopressin and angiotensin II in cardiovascular responses to combined acute hypoxemia and hypercapnic acidosis in conscious dogs. [PDF]
, 1984 Charles E. Rose +4 more
openalex +1 more source
Angiotensin II and Aldosterone Increase with Fasting in Breeding Adult Male Northern Elephant Seals (Mirounga angustirostris) [PDF]
, 2006 The renin‐angiotensin‐aldosterone system (RAAS) appears to contribute significantly to osmoregulation of fasting northern elephant seal (Mirounga angustirostris) pups; however, RAAS has not been characterized in fasting adult seals. Therefore, this study
Crocker, Daniel E. E. +3 more
core +1 more source