Results 91 to 100 of about 41,836 (256)
eLife, 2021 Insulin-induced hypoglycemia is a major treatment barrier in type-1 diabetes (T1D). Accordingly, it is important that we understand the mechanisms regulating the circulating levels of glucagon.
Angela Kim +23 more
doaj +1 more source
Altered agonist sensitivity of a mutant V2 receptor suggests a novel therapeutic strategy for nephrogenic diabetes insipidus. [PDF]
, 2014 Loss of function mutations of the type 2 vasopressin receptor (V2R) in kidney can lead to nephrogenic diabetes insipidus (NDI). We studied a previously described, but uncharacterized mutation of V2R (N321K missense mutation) of an NDI patient.
Balla, András +5 more
core +1 more source
Biochemistry, 2015 The evolutionarily conserved DRY motif at the end of the third helix of rhodopsin-like, class-A G protein-coupled receptors (GPCRs) is a major regulator of receptor stability, signaling activity, and β-arrestin-mediated internalization.
Martina S. Burczyk +6 more
semanticscholar +1 more source
Platelet Levels Associated With Bleeding Risk for Dental Interventions: A Systematic Review
Oral Diseases, EarlyView.ABSTRACT Objectives To evaluate evidence in relation to postoperative bleeding in humans aged ≥ 16 with preoperative platelet counts < 50,000/μL, compared to those above, undergoing dental interventions. Methods Quantitative synthesis without meta‐analysis was conducted through an electronic search conducted on Ovid MEDLINE and Embase from 1946 to ...
Guang Xu David Lim +3 more
wiley +1 more source
Vasopressin-Independent Regulation of Aquaporin-2 by Tamoxifen in Kidney Collecting Ducts
Frontiers in Physiology, 2019 Arginine vasopressin (AVP) mediates water reabsorption in the kidney collecting ducts through regulation of aquaporin-2 (AQP2). Also, estrogen has been known to regulate AQP2.
Stine Julie Tingskov +9 more
doaj +1 more source
Arginine vasopressin, via activation of post-junctional V1 receptors, induces contractile effects in mouse distal colon [PDF]
, 2013 The aim of this study was to analyze whether arginine vasopressin (AVP) may be considered a modulator of intestinal motility. In this view, we evaluated, in vitro, the effects induced by exogenous administration of AVP on the contractility of mouse ...
AUTERI, Michelangelo +4 more
core +1 more source
Engineered surface strategies to manage dental implant‐related infections
Periodontology 2000, EarlyView.Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza +7 more
wiley +1 more source
Journal of Clinical Endocrinology and Metabolism, 2019 CONTEXT Although the physiology of sodium, water and arginine vasopressin (AVP), also known as antidiuretic hormone (ADH), has long been known, accumulating data suggest that this system operates as a more complex network than previously thought ...
M. Kanbay +10 more
semanticscholar +1 more source
Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications
Experimental Physiology, EarlyView.Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó +1 more
wiley +1 more source
Rare but relevant: MDMA and hyponatraemia
Addiction, Volume 121, Issue 3, Page 713-718, March 2026.Abstract Conventionally used for its stimulant, empathogenic and entactogenic effects, 3,4‐methylenedioxymethamphetamine (MDMA, ecstasy) is one of the most commonly used psychoactive drugs, specifically among young adults and in nightlife and recreational party contexts.
Maria Rita Garcia +2 more
wiley +1 more source