Results 101 to 110 of about 41,836 (256)

Neural mechanisms of AVPR1A RS3-RS1 haplotypes that impact verbal learning and memory

NeuroImage, 2020
Converging evidence from both human and animal studies has highlighted the pervasive role of the neuropeptide arginine vasopressin (AVP), which is mediated by arginine vasopressin receptor 1A (AVPR1A), in both social and nonsocial learning and memory ...
Yan Zhang, Dan Zhu, Peng Zhang, Wei Li, Wen Qin, Feng Liu, Jiayuan Xu, Qiang Xu, Junping Wang, Zhaoxiang Ye, Chunshui Yu   +10 more
doaj   +1 more source

Choroid plexus alterations in long COVID and their associations with Alzheimer's disease risks

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Choroid plexus (ChP) enlargement is a neuroimaging biomarker of neuroinflammation and neurodegeneration. However, evidence of ChP structural and perfusion alterations in long coronavirus disease (COVID) and their clinical relevance remains limited.
Huize Pang, Jennifer Frontera, Li Jiang, Chenyang Li, Allal Boutajangout, Zhe Sun, Ludovic Debure, Mobeena Ghuman, Alok Vedvyas, Arjun V. Masurkar, Thomas Wisniewski, Yulin Ge   +11 more
wiley   +1 more source

Novel de novo AVPR2 Variant in a Patient with Congenital Nephrogenic Diabetes Insipidus

Case Reports in Nephrology and Dialysis, 2017
Early diagnosis and treatment of congenital nephrogenic diabetes insipidus (CNDI) are essential due to the risk of intellectual disability caused by repeated episodes of dehydration and rapid rehydration.
Shivani Joshi, Per Brandstrom, Niels Gregersen, Søren Rittig, Jane Hvarregaard Christensen   +4 more
doaj   +1 more source

Nephrogenic syndrome of inappropriate antidiuresis secondary to an activating mutation in the arginine vasopressin receptor AVPR2. [PDF]

, 2016
CONTEXT: Nephrogenic syndrome of inappropriate antidiuresis (NSIAD), resulting from activating mutations in the arginine vasopressin receptor type 2 (AVPR2), is a rare cause of hyponatraemia.
Adrogué, Audet, Ball, Bes, Bockenhauer, Brachet, Carpentier, Clayton, Cowen, Decaux, Erdélyi, Feldman, Fu, Gitelman, Gupta, Hinchliffe, Hu, Huang, Kelley, Marcialis, Ranchin, Renneboog, Robertson, Robertson, Rochdi, Rovati, Soule, Spanakis, Spasovski, Spiegel, Tenenbaum, Vandergheynst, Vassart, Verbalis, Wald, Zerbe   +35 more
core   +2 more sources

Novel mutation in the AVPR2 gene in a Danish male with nephrogenic diabetes insipidus caused by ER retention and subsequent lysosomal degradation of the mutant receptor

NDT plus, 2011
Mutations in the arginine vasopressin receptor 2 (AVPR2) gene can cause X-linked nephrogenic diabetes insipidus (NDI) characterized by the production of large amounts of urine and an inability to concentrate urine in response to the antidiuretic hormone ...
L. N. Nejsum, T. M. Christensen, J. Robben, G. Milligan, P. Deen, D. Bichet, K. Levin   +6 more
semanticscholar   +1 more source

Deceptive beauty of non‐natural structures

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Structures of proteins and multiprotein complexes are considered landmark achievements. However, in many cases, mutant proteins are used for structural work. Even when wild type proteins are used, crystallization or complex formation for cryoEM is performed in highly nonphysiological conditions.
Vsevolod V. Gurevich, Eugenia V. Gurevich   +1 more
wiley   +1 more source

Antidiuretic Effects of a Novel Nonpeptide Vasopressin V2-Receptor Agonist, OPC-51803, Administered Orally to Dogs

Journal of Pharmacological Sciences, 2004
We elucidated the pharmacological properties of a novel nonpeptide vasopressin V2-receptor agonist, OPC-51803 ((5R)-2-[1-(2-chloro-4-(1-pyrrolidinyl)benzoyl-2,3,4,5-tetra-hydro-1H-1-benzazepine-5-yl]-N-isopropylacetamide), via both in vitro binding ...
Shigeki Nakamura, Takahiro Hirano, Toshiyuki Onogawa, Shuji Itoh, Ayako Hashimoto, Yoshitaka Yamamura, Kazumi Kondo, Toyoki Mori, Toshimi Kambe   +8 more
doaj   +1 more source

Contractile responses of human thyroid arteries to vasopressin [PDF]

, 2013
Aims: In the present study we investigated the intervention of nitric oxide and prostacyclin in the responses to vasopressin of isolated thyroid arteries obtained from multi-organ donors.
Aldasoro Celaya, Martín, Lluch López, Salvador, Martínez León, Juan Bautista, Mauricio Aviñó, María Dolores, Medina Bessó, Pascual, Segarra Irles, Gloria Vicenta, Vila Salinas, José María   +6 more
core   +2 more sources

Liquid–Liquid Phase Separation in Major Hallmarks of Cancer

Cell Proliferation, Volume 59, Issue 2, February 2026.
Aberrant condensates formed through phase separation are involved in the dysregulation of various critical cellular processes, including genome stability, transcriptional regulation and signal transduction, thereby promoting malignant transformation and the acquisition of multiple cancer hallmarks.
Chen‐chen Xie, Ting Wang, Xin‐ran Liu, Yan Wang, Qin Dang, Tian Ding, Jia‐qi Xu, Xian‐jun Yu, Hai Lin, Xiao‐wu Xu, Yi Qin   +10 more
wiley   +1 more source

Androgen Receptor and Vasopressin Receptor (AVPR1a) Genetic Polymorphisms are not associated with Marital Status or Fertility among Ariaal Men of Northern Kenya [PDF]

, 2009
A growing body of scholarship implicates testosterone and vasopressin in male reproductive behavior, including in humans. Since hormones exert their effects through their respective receptors, an open question has been whether genetic polymorphisms in ...
Benjamin C. Campbell, Dan T. A. Eisenberg, Peter B. Gray   +2 more
core   +2 more sources