Results 11 to 20 of about 41,836 (256)

Inner Ear Arginine Vasopressin-Vasopressin Receptor 2-Aquaporin 2 Signaling Pathway Is Involved in the Induction of Motion Sickness [PDF]

The Journal of Pharmacology and Experimental Therapeutics, 2020
It has been identified that arginine vasopressin (AVP), vasopressin receptor 2(V2R), and the aquaporin 2 (AQP2) signaling pathway in the inner ear play important roles in hearing and balance functions through regulating the endolymph equilibrium; however,
Lihua Xu, Yao Yang, Hongxia Liu, Shuifeng Xiao, Qiu Wen-xia, Jin‐Xing Wang, Chenchen Zhao, Yuan-Hong Gui, Guizhu Liu, Bin Peng, Xia Li, Guohua Wang, Xin Zhou, Zheng‐Lin Jiang   +13 more
semanticscholar   +4 more sources

Identification of mutations in the arginine vasopressin receptor 2 gene causing nephrogenic diabetes insipidus in Chinese patients [PDF]

Journal of Human Genetics, 2002
Congenital nephrogenic diabetes insipidus (NDI) is, in most instances, a rare X-linked recessive renal disorder (MIM 304800) characterized by the clinical symptoms of polyuria, polydipsia, and dehydration. The X-linked NDI is associated with mutations of the arginine vasopressin receptor type 2 (AVPR2) gene, which results in resistance to the ...
Chia‐Hsiang Chen, W.-Y. Chen, Honglin Liu, Tianyu Liu, A.-P. Tsou, C.-Y. Lin, Ting‐Hsing Chao, Y. Qi, K J Hsiao   +8 more
semanticscholar   +4 more sources

Identification of a novel X-linked arginine-vasopressin receptor 2 mutation in nephrogenic diabetes insipidus: Case report and pedigree analysis. [PDF]

Medicine (Baltimore), 2019
Abstract Introduction: The clinical and genetic characteristics of nephrogenic diabetes insipidus (NDI) were described via assessing 2 cases of NDI patients from a Chinese family. Patient concerns: Two patients who manifest polyuria and polydipsia were admitted to hospital
Peng D, Dai Y, Xu X.
europepmc   +4 more sources

CHEMICAL CHAPERONE EFFECTS ON ARGININE-VASOPRESSIN RECEPTOR 2 MUTANTS

Hacettepe Journal of Biology and Chemistry, 2021
Improper folding of the mutant proteins may finally cause several conformational diseases such as Nephrogenic Diabetes Insipidus (NDI). In recent years, as a therapeutic strategy, chaperone treatment for such diseases is among current issues. In our study, we aimed to analyze the effect of several chemical chaperones on mutant V2 receptors which cause ...
Beril Erdem Tuncdemır, Tuğçe Karaduman, Merve Özcan Türkmen, Dilara Şahin, Hatice Mergen, Emel Sağlar Özer   +5 more
semanticscholar   +6 more sources

Identification of a Novel Arginine Vasopressin Receptor 2 Mutation (p.V183M) in a Chinese Family with Nephrogenic Diabetes Insipidus. [PDF]

Mol Syndromol, 2020
Loss of function of arginine vasopressin receptor 2 (AVPR2) may affect the recognition and binding of arginine vasopressin (AVP) which, in turn, may prevent the activation of Gs/adenylate cyclase and reduce the reabsorption of water by renal tubules and combined tubes.
Liu JS, Huang H, Jin JY, Du R, Wang CY, Fan LL.   +5 more
europepmc   +5 more sources

Opposite Effects of Central Amygdaloid Vasopressin and Oxytocin on the Regulation of Conditioned Stress Responses in Male Rats [PDF]

Journal of Thrombosis and Haemostasis, 1992
AIMS/HYPOTHESIS: Vasopressin plays a role in osmoregulation, glucose homeostasis and inflammation. Therefore, plasma copeptin, the stable C-terminal portion of the precursor of vasopressin, has strong potential as a biomarker for the cardiometabolic ...
Bohus, B.,, Driscoll, P.,, Koolhaas, J.M.,, Roozendaal, B.,, Schoorlemmer, G.H.M.,, Sluyter, S.,, Wiersma, A.,   +6 more
core   +39 more sources

Hypothalamic kinin B1 receptor mediates orexin system hyperactivity in neurogenic hypertension

Scientific Reports, 2021
Brain orexin system hyperactivity contributes to neurogenic hypertension. We previously reported upregulated neuronal kinin B1 receptor (B1R) expression in hypertension.
Rohan Umesh Parekh, Acacia White, Korin E. Leffler, Vinicia C. Biancardi, Jeffrey B. Eells, Abdel A. Abdel-Rahman, Srinivas Sriramula   +6 more
doaj   +2 more sources

Glucocorticoids Reverse Diluted Hyponatremia Through Inhibiting Arginine Vasopressin Pathway in Heart Failure Rats

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Arginine vasopressin dependent antidiuresis plays a key role in water‐sodium retention in heart failure. In recent years, the role of glucocorticoids in the control of body fluid homeostasis has been extensively investigated.
Xiaoran Zhu, Yaomeng Huang, Shuyu Li, Ning Ge, Tongxin Li, Yu Wang, Kunshen Liu, Chao Liu   +7 more
doaj   +2 more sources

A Novel Missense Mutation of Arginine Vasopressin Receptor 2 in a Chinese Family with Congenital Nephrogenic Diabetes Insipidus: X-Chromosome Inactivation in Female CNDI Patients with Heterozygote 814A>G Mutation. [PDF]

Biomed Res Int, 2022
Zang L, Gong Y, Li Y, Dou J, Lyu Z, Su X, Zhang Y, Mu Y.   +7 more
europepmc   +2 more sources

New insights into the transcriptional regulation of aquaporin-2 and the treatment of X-linked hereditary nephrogenic diabetes insipidus

Kidney Research and Clinical Practice, 2019
The kidney collecting duct (CD) is a tubular segment of the kidney where the osmolality and final flow rate of urine are established, enabling urine concentration and body water homeostasis.
Hyun Jun Jung, Tae-Hwan Kwon
doaj   +2 more sources