Results 31 to 40 of about 41,836 (256)

Arginine Vasopressin Enhances Cell Survival via a G Protein–Coupled Receptor Kinase 2/β-Arrestin1/Extracellular-Regulated Kinase 1/2–Dependent Pathway in H9c2 Cells [PDF]

Molecular Pharmacology, 2013
Circulating levels of arginine vasopressin (AVP) are elevated during hypovolemia and during cardiac stress. AVP activates arginine vasopressin type 1A (V(1A))/Gα(q)-coupled receptors in the heart and vasculature and V(2)/Gα(s)-coupled receptors in the kidney.
Weizhong Zhu, Douglas G. Tilley, Valerie D. Myers, Ryan C. Coleman, Arthur M. Feldman   +4 more
openalex   +4 more sources

An infant with congenital nephrogenic diabetes insipidus presenting with hypercalcemia and hyperphosphatemia

Endocrinology, Diabetes & Metabolism Case Reports, 2021
We report a male infant with congenital nephrogenic diabetes insipidus (NDI) who presented with hypercalcemia and hyperphosphatemia since birth. Serum sodium started to increase at 39 days. Although there was no polyuria, urine osmolality was 71 mOsm/kg,
Katsuo Tao, Midori Awazu, Misa Honda, Hironori Shibata, Takayasu Mori, Shinichi Uchida, Tomonobu Hasegawa, Tomohiro Ishii   +7 more
doaj   +1 more source

V2 vasopressin receptor mutations: future personalized therapy based on individual molecular biology

Frontiers in Endocrinology, 2023
The diluting and concentrating function of the kidney plays a crucial role in regulating the water homeostasis of the body. This function is regulated by the antidiuretic hormone, arginine vasopressin through the type 2 vasopressin receptor (V2R ...
László Sándor Erdélyi, László Hunyady, László Hunyady, András Balla, András Balla   +4 more
doaj   +1 more source

Identification and functional characterization of arginine vasopressin receptor 1A : atypical chemokine receptor 3 heteromers in vascular smooth muscle [PDF]

Open Biology, 2018
Recent observations suggest that atypical chemokine receptor (ACKR)3 and chemokine (C-X-C motif) receptor (CXCR)4 regulate human vascular smooth muscle function through hetero-oligomerization with α1-adrenoceptors. Here, we show that ACKR3 also regulates
Lauren J. Albee, Heather M. LaPorte, Xianlong Gao, Jonathan M. Eby, You-Hong Cheng, Amanda M. Nevins, Brian F. Volkman, Vadim Gaponenko, Matthias Majetschak   +8 more
doaj   +1 more source

Neonatal AVPR1a Methylation and In-Utero Exposure to Maternal Smoking

Toxics, 2023
(1) Introduction: Epigenetic changes have been proposed as a biologic link between in-utero exposure to maternal smoking and health outcomes. Therefore, we examined if in-utero exposure to maternal smoking was associated with infant DNA methylation (DNAm)
Nichole Nidey, Katherine Bowers, Lili Ding, Hong Ji, Robert T. Ammerman, Kimberly Yolton, E. Melinda Mahabee-Gittens, Alonzo T. Folger   +7 more
doaj   +1 more source

Pharmacologic management of nocturnal polyuria: a contemporary assessment of efficacy, safety, and progress toward individualized treatment

Therapeutic Advances in Urology, 2021
This narrative review synthesizes current evidence on the medical management of nocturnal polyuria, including antidiuretic replacement therapy as well as other emerging modalities, with particular emphasis on areas of active investigation and future ...
Thomas F. Monaghan, Jeffrey P. Weiss, Karel Everaert, Alan J. Wein   +3 more
doaj   +1 more source

Three Pediatric Patients with Congenital Nephrogenic Diabetes Insipidus due to AVPR2 Nonsense Mutations and Different Clinical Manifestations: A Case Report

Case Reports in Nephrology and Dialysis, 2023
Congenital nephrogenic diabetes insipidus (CNDI), a rare hereditary disorder, is characterized by the inability of the kidneys to concentrate urine in response to the antidiuretic hormone arginine vasopressin (AVP); as a result, large volumes of ...
Hijiri Watanabe, Hiroshi Tamura, Keishiro Furuie, Shohei Kuraoka, Hitoshi Nakazato   +4 more
doaj   +1 more source

A Novel Mutation of the Arginine Vasopressin Receptor 2 Gene in a Patient with Congenital Nephrogenic Diabetes Insipidus

Clinical Pediatric Endocrinology, 2005
We have identified a novel mutation of the arginine vasopressin receptor 2 (AVPR2) gene in a case of congenital X-linked nephrogenic diabetes insipidus (NDI). The patient was a 2-mo-old Japanese boy with persistent fever and failure to thrive. He was diagnosed as having congenital NDI by clinical and laboratory findings. Molecular analysis demonstrated
Asako Tajima, Ichiro Miyata, Akira Katayama, Shigeru Toyoda, Yoshikatsu Eto   +4 more
openalex   +4 more sources

Functional Rescue of a Nephrogenic Diabetes Insipidus Causing Mutation in the V2 Vasopressin Receptor by Specific Antagonist and Agonist Pharmacochaperones

Frontiers in Pharmacology, 2022
The urine concentrating function of the kidney is essential to maintain the water homeostasis of the human body. It is mainly regulated by the arginine-vasopressin (AVP), which targets the type 2 vasopressin receptor (V2R) in the kidney. The inability of
Laura Szalai, Laura Szalai, András Sziráki, László Sándor Erdélyi, Kinga Bernadett Kovács, Miklós Tóth, András Dávid Tóth, András Dávid Tóth, András Dávid Tóth, Gábor Turu, Gábor Turu, Dominique Bonnet, Bernard Mouillac, László Hunyady, László Hunyady, László Hunyady, András Balla, András Balla   +17 more
doaj   +1 more source

Effect of arginine vasopressin on the canine epicardial coronary artery: experiments on V1-receptor-mediated production of nitric oxide

Arquivos Brasileiros de Cardiologia, 2003
OBJECTIVE: To determine whether arginine vasopressin releases endothelium-derived nitric oxide (EDNO) from the epicardial coronary artery. METHODS: We studied segments of canine left circumflex coronary arteries suspended in organ chambers to measure ...
Paulo Roberto B. Evora, Paul J. Pearson, Alfredo J. Rodrigues, Fernanda Viaro, Hartzell V. Schaff   +4 more
doaj   +1 more source