Results 81 to 90 of about 41,836 (256)

Correlation analysis of AVPR1a and AVPR2 with abnormal water and sodium and potassium metabolism in rats

open access: yesOpen Life Sciences
In clinical practice, an increasing number of patients exhibit concurrent cardiac and renal dysfunction, known as “cardiorenal syndrome,” where each condition exacerbates the other, resulting in poorer patient prognosis.
Sun Kun, Qiu Yingzhu, Sun Yao
doaj   +1 more source

Retention of differentiated properties in an established dog kidney epithelial cell line (MDCK). [PDF]

open access: yes, 1979
Madin-Darby canine kidney (MDCK) cells grown in tissue culture have the morphological properties of distal tubular epithelial cells, form tight junctions, and lack several proximal tubular enzyme markers.
Chuman, LM   +3 more
core  

Compartmentalisation in cAMP signalling: A phase separation perspective

open access: yesBritish Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Effect of vasopressin on the expression of genes for key enzymes of interstitial hyaluronan turnover and concentration ability in WAG rat kidneys

open access: yesВавиловский журнал генетики и селекции, 2016
In mammals, arginine-vasopressin (AVP) is a major hormone involved in the regulation of renal water reabsorption, acting via an increase in the osmotic permeability of the collecting duct epithelium.
L. N. Ivanova   +3 more
doaj   +1 more source

Restoration of peripheral V2 receptor vasopressin signaling fails to correct behavioral changes in Brattleboro rats. [PDF]

open access: yes, 2014
Beside its hormonal function in salt and water homeostasis, vasopressin released into distinct brain areas plays a crucial role in stress-related behavior resulting in the enhancement of an anxious/depressive-like state.
Anna Fodor   +7 more
core   +1 more source

Investigating the Multitarget Mechanism of Traditional Chinese Medicine Prescription for Cancer-Related Pain by Using Network Pharmacology and Molecular Docking Approach

open access: yesEvidence-Based Complementary and Alternative Medicine, 2020
Gu-tong formula (GTF) has achieved good curative effects in the treatment of cancer-related pain. However, its potential mechanisms have not been explored.
Jin-yuan Chang   +5 more
semanticscholar   +1 more source

First Detection of Lactococcus formosensis subsp. formosensis in Rainbow Trout (Oncorhynchus mykiss) in Europe

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Lactococcus garvieae, Lactococcus petauri and Lactococcus formosensis are etiological agents of piscine lactococcosis, a disease reported in Italy since the early 1990s and linked to significant aquaculture losses. To the best of our knowledge, this study reports the first detection of L. formosensis subsp. formosensis in farmed rainbow trout (
Silvia Colussi   +12 more
wiley   +1 more source

Effects of YM087 and VPA985 on the T237M mutant receptor functionality in nephrogenic diabetes insipidus

open access: yesTürk Biyokimya Dergisi
Mutations detected in the AVPR2 gene (arginine vasopressin type 2 receptor) are known to cause nephrogenic diabetes insipidus (NDI). Several pharmacological chaperones (PCs) target misfolded AVPR2 proteins and rescue them from the quality control system ...
Avcu Elif Merve   +2 more
doaj   +1 more source

NMDA Receptor in Vasopressin 1b Neurons Is Not Required for Short-Term Social Memory, Object Memory or Aggression

open access: yesFrontiers in Behavioral Neuroscience, 2019
The arginine vasopressin 1b receptor (Avpr1b) plays an important role in social behaviors including aggression, social learning and memory. Genetic removal of Avpr1b from mouse models results in deficits in aggression and short-term social recognition in
Sarah K. Williams Avram   +15 more
doaj   +1 more source

NADPH oxidase 4 deficiency reduces aquaporin-2 mRNA expression in cultured renal collecting duct principal cells via increased PDE3 and PDE4 activity. [PDF]

open access: yesPLoS ONE, 2014
The final control of renal water reabsorption occurs in the collecting duct (CD) and relies on regulated expression of aquaporin-2 (AQP2) in principal CD cells.
Eric Féraille   +7 more
doaj   +1 more source

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