Results 41 to 50 of about 555,573 (335)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

A stabilized low-frequency alternating-current electric arc [PDF]

open access: yes, 1970
Establishing an arc between water-cooled tungsten-tipped electrodes, maintaining the arc along the centerline of a central jet of argon gas, and surrounding the argon jet with a coaxial sheath of nitrogen stabilizes operation of a low-frequency ac ...
Lanzo, C. D.
core   +1 more source

Low temperature scattering with the R-matrix method: argon-argon scattering

open access: yes, 2019
Results for elastic atom-atom scattering are obtained as a first practical application of RmatReact, a new code for generating high-accuracy scattering observables from potential energy curves.
McKemmish, Laura K.   +3 more
core   +1 more source

Volcanism records plate thinning driven rift localization in Afar (Ethiopia) since 2-2.5 million years ago

open access: yesCommunications Earth & Environment
Magma-rich continental rifting and breakup commonly show complex distributions of volcanism, potentially due to both plume and rifting controls. As such, interpreting the main controls on the spatial evolution of magmatism is debated, as is the point at ...
Gianmaria Tortelli   +9 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Preliminary test results of LAr prototype detector

open access: yes, 2016
WIMPs are a well-motivated galactic dark matter candidate. Liquid argon (LAr) is an attractive target for the direct detection of WIMPs. The LAr prototype detector is designed to study the technology and property of LAr detector.
Guan, Meng-Yun   +7 more
core   +1 more source

Static and dynamic aspects of coupling between creep behavior and oxidation on MC2 single crystal superalloy at 1150 °C [PDF]

open access: yes, 2005
Creep tests were performed on thin wall specimens made of MC2 single crystal superalloy at 1150 °C and under controlled atmosphere. The results highlight the deleterious oxidation effect on creep properties.
Andrieu, Eric   +3 more
core   +2 more sources

ORGANIZATION OF PROTECTION MECHANISMS FOR CLOUD STORAGE SERVICES

open access: yesДоклады Белорусского государственного университета информатики и радиоэлектроники, 2019
Providing effective security mechanisms is an important requirement to any secure cloud solution. In this sense, it's proposed to use a hybrid approach to cloud security that includes both warning and detection mechanisms in order to minimize the ...
T. .. Galibus   +7 more
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

A simplified hydrokinetic model for a steady‐state microwave discharge sustained by traveling waves at atmospheric pressure conditions [PDF]

open access: yes, 1995
The properties of a microwave‐induced argon plasma produced by traveling surface wave at atmospheric pressure are investigated theoretically. A hydrokinetic model is elaborated to obtain the nonequilibrium one‐dimensional profiles of electron temperature
Cotrino Bautista, José   +2 more
core   +1 more source

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