Results 51 to 60 of about 150,202 (254)

Volcanism records plate thinning driven rift localization in Afar (Ethiopia) since 2-2.5 million years ago

open access: yesCommunications Earth & Environment
Magma-rich continental rifting and breakup commonly show complex distributions of volcanism, potentially due to both plume and rifting controls. As such, interpreting the main controls on the spatial evolution of magmatism is debated, as is the point at ...
Gianmaria Tortelli   +9 more
doaj   +1 more source

INVESTIGATION OF THE ROLE OF LIME UNDER SLAGGING AND INERT-GAS SECONDARY STEEL REFINING

open access: yesAdvanced Engineering Research, 2013
It is shown that the creation of such technologies is caused by the necessity of making standard high-quality steel in composition and temperature. The secondary steel refining provides these conditions and, consequently, the efficient operation of the ...
Denis Anatolyevich Bakhayev   +3 more
doaj   +1 more source

Effects of nitrogen gas flushing in comparison with argon on rumen fermentation characteristics in in vitro studies

open access: yesJournal of Animal Science and Technology, 2020
In rumen in vitro experiments, although nitrogen gas (N2) flushing has been widely used, its effects on rumen fermentation characteristics are not clearly determined.
KiYeon Park, HongGu Lee
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

A New Non-Extensive Equation of State for the Fluid Phases of Argon, Including the Metastable States, from the Melting Line to 2300 K and 50 GPa

open access: yesFluids
A new equation of state for argon was developed with the view of extending the range of validity of the equation of state previously proposed by Tegeler et al.
Frédéric Aitken   +2 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

A pulse of mid-Pleistocene rift volcanism in Ethiopia at the dawn of modern humans

open access: yesNature Communications, 2016
Past volcanic eruptions along the densely populated Ethiopian Rift valley remain poorly constrained despite the present day hazard. Hutchison et al.
William Hutchison   +10 more
doaj   +1 more source

Influence of the CO2 Content in Shielding Gas on the Temperature of the Shielding Gas Nozzle during GMAW Welding

open access: yesJournal of Manufacturing and Materials Processing, 2020
Gas metal arc welding torches are commonly chosen based on their current-carrying capacity. It is known that the current-carrying capacity of welding torches under CO2 is usually higher than under argon dominated shielding gases. In this publication, the
Martin Lohse   +3 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

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