Results 41 to 50 of about 234,919 (286)
ObjectiveThe aim of this study was to design and optimize a cold atmospheric plasma (CAP) device that could be applied in an oral environment and to study its effects on plaque biofilm metabolism and regrowth, as well as microbial flora composition and ...
Haowei Zhao +6 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
The prospect of Sunni-Alevi inter-Muslim dialogue can be a sustained long-term project and is not a novel concept in Turkey: there has been official and academic activity in this regard.
Kemal Enz ARGON
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
ORGANIZATION OF PROTECTION MECHANISMS FOR CLOUD STORAGE SERVICES
Providing effective security mechanisms is an important requirement to any secure cloud solution. In this sense, it's proposed to use a hybrid approach to cloud security that includes both warning and detection mechanisms in order to minimize the ...
T. .. Galibus +7 more
doaj
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Magma-rich continental rifting and breakup commonly show complex distributions of volcanism, potentially due to both plume and rifting controls. As such, interpreting the main controls on the spatial evolution of magmatism is debated, as is the point at ...
Gianmaria Tortelli +9 more
doaj +1 more source
INVESTIGATION OF THE ROLE OF LIME UNDER SLAGGING AND INERT-GAS SECONDARY STEEL REFINING
It is shown that the creation of such technologies is caused by the necessity of making standard high-quality steel in composition and temperature. The secondary steel refining provides these conditions and, consequently, the efficient operation of the ...
Denis Anatolyevich Bakhayev +3 more
doaj +1 more source
In rumen in vitro experiments, although nitrogen gas (N2) flushing has been widely used, its effects on rumen fermentation characteristics are not clearly determined.
KiYeon Park, HongGu Lee
doaj +1 more source

