Results 41 to 50 of about 562,200 (340)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

INVESTIGATION OF THE ROLE OF LIME UNDER SLAGGING AND INERT-GAS SECONDARY STEEL REFINING

Advanced Engineering Research, 2013
It is shown that the creation of such technologies is caused by the necessity of making standard high-quality steel in composition and temperature. The secondary steel refining provides these conditions and, consequently, the efficient operation of the ...
Denis Anatolyevich Bakhayev, Alexander Ivanovich Kochetov, Alexander Yuryevich Kem, Alexey Alexandrovich Ansimov   +3 more
doaj   +1 more source

Effects of nitrogen gas flushing in comparison with argon on rumen fermentation characteristics in in vitro studies

Journal of Animal Science and Technology, 2020
In rumen in vitro experiments, although nitrogen gas (N2) flushing has been widely used, its effects on rumen fermentation characteristics are not clearly determined.
KiYeon Park, HongGu Lee
doaj   +1 more source

ArDM: first results from underground commissioning

, 2013
The Argon Dark Matter experiment is a ton-scale double phase argon Time Projection Chamber designed for direct Dark Matter searches. It combines the detection of scintillation light together with the ionisation charge in order to discriminate the ...
Badertscher, A., Bay, F., Bourgeois, N., Cantini, C., Curioni, A., Daniel, M., Degunda, U., Di Luise, S., Epprecht, L., Gendotti, A., Horikawa, S., Knecht, L., Lussi, D., Maire, G., Montes, B., Murphy, S., Natterer, G., Nguyen, K., Nikolics, K., Periale, L., Ravat, S., Resnati, F., Romero, L., Rubbia, A., Santorelli, R., Sergiampietri, F., Sgalaberna, D., Viant, T., Wu, S.   +28 more
core   +1 more source

A simplified hydrokinetic model for a steady‐state microwave discharge sustained by traveling waves at atmospheric pressure conditions [PDF]

, 1995
The properties of a microwave‐induced argon plasma produced by traveling surface wave at atmospheric pressure are investigated theoretically. A hydrokinetic model is elaborated to obtain the nonequilibrium one‐dimensional profiles of electron temperature
Cotrino Bautista, José, Cotrino Bautista, José (Coordinador), Gordillo Vázquez, Francisco José   +2 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Volcanism records plate thinning driven rift localization in Afar (Ethiopia) since 2-2.5 million years ago

Communications Earth & Environment
Magma-rich continental rifting and breakup commonly show complex distributions of volcanism, potentially due to both plume and rifting controls. As such, interpreting the main controls on the spatial evolution of magmatism is debated, as is the point at ...
Gianmaria Tortelli, Anna Gioncada, Carolina Pagli, Dan N. Barfod, Giacomo Corti, Federico Sani, Darren F. Mark, Ross C. Dymock, Ermias F. Gebru, Derek Keir   +9 more
doaj   +1 more source

Characteristics and performance study of mass spectrometer residual gas analyzers [PDF]

, 1975
Types of instruments studied were magnetic sector, omegatron, quadrupole, and monopole. Experimental results obtained included absolute sensitivity to argon, relative sensitivity to ten gases (hydrogen, helium, neon, nitrogen, carbon monoxide, oxygen ...
Hultzman, W. W.
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

ORGANIZATION OF PROTECTION MECHANISMS FOR CLOUD STORAGE SERVICES

Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019
Providing effective security mechanisms is an important requirement to any secure cloud solution. In this sense, it's proposed to use a hybrid approach to cloud security that includes both warning and detection mechanisms in order to minimize the ...
T. .. Galibus, V. .. Krasnoproshin, P. V. Thiago, T. DE. Rafael, P. C. João, P. DE. Edison, Z. Anton, H. E. Vissia   +7 more
doaj