Results 41 to 50 of about 234,919 (286)

The effect of argon cold atmospheric plasma on the metabolism and demineralization of oral plaque biofilms

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
ObjectiveThe aim of this study was to design and optimize a cold atmospheric plasma (CAP) device that could be applied in an oral environment and to study its effects on plaque biofilm metabolism and regrowth, as well as microbial flora composition and ...
Haowei Zhao   +6 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Turkish Sunni-Alevi Dialogue Methodology: A Proposal for Projects Using Qur'an Citations in Classical Alevi Sources

open access: yesMütefekkir, 2015
The prospect of Sunni-Alevi inter-Muslim dialogue can be a sustained long-term project and is not a novel concept in Turkey: there has been official and academic activity in this regard.
Kemal Enz ARGON
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

ORGANIZATION OF PROTECTION MECHANISMS FOR CLOUD STORAGE SERVICES

open access: yesДоклады Белорусского государственного университета информатики и радиоэлектроники, 2019
Providing effective security mechanisms is an important requirement to any secure cloud solution. In this sense, it's proposed to use a hybrid approach to cloud security that includes both warning and detection mechanisms in order to minimize the ...
T. .. Galibus   +7 more
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Volcanism records plate thinning driven rift localization in Afar (Ethiopia) since 2-2.5 million years ago

open access: yesCommunications Earth & Environment
Magma-rich continental rifting and breakup commonly show complex distributions of volcanism, potentially due to both plume and rifting controls. As such, interpreting the main controls on the spatial evolution of magmatism is debated, as is the point at ...
Gianmaria Tortelli   +9 more
doaj   +1 more source

INVESTIGATION OF THE ROLE OF LIME UNDER SLAGGING AND INERT-GAS SECONDARY STEEL REFINING

open access: yesAdvanced Engineering Research, 2013
It is shown that the creation of such technologies is caused by the necessity of making standard high-quality steel in composition and temperature. The secondary steel refining provides these conditions and, consequently, the efficient operation of the ...
Denis Anatolyevich Bakhayev   +3 more
doaj   +1 more source

Effects of nitrogen gas flushing in comparison with argon on rumen fermentation characteristics in in vitro studies

open access: yesJournal of Animal Science and Technology, 2020
In rumen in vitro experiments, although nitrogen gas (N2) flushing has been widely used, its effects on rumen fermentation characteristics are not clearly determined.
KiYeon Park, HongGu Lee
doaj   +1 more source

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