Results 111 to 120 of about 4,006,141 (333)

Discussion: Darwin's argument in the origin [PDF]

open access: yes, 1992
Various claims have been made, recently, that Darwin's argumentation in the Origin instantiates and so supports some general philosophical proposal about scientific theorizing, for example, the "semantic view".
Hodge, M.J.S.
core  

Why is the ground state electron configuration for Lithium $1s^22s$ ?

open access: yes, 2012
The electronic ground state for Lithium is $1s^22s$, and not $1s^22p$. The traditional argument for why this is so is based on a screening argument that claims that the $2p$ electron is better shielded by the $1s$ electrons, and therefore higher in ...
Marsiglio, F., Stacey, W. S.
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Reflections on Minimal Adversariality

open access: yesInformal Logic, 2021
Beginning with my 1999 account in The Philosophy of Argument, this essay explores views about adversariality in argument.  Although my distinction between minimal and ancillary adversariality is widely accepted, there are flaws in my defense of the claim
Trudy Govier
doaj  

Multi-argument classification for semantic role labeling [PDF]

open access: yes, 2008
This paper describes a Multi-Argument Classification (MAC) approach to Semantic Role Labeling. The goal is to exploit dependencies between semantic roles by simultaneously classifying all arguments as a pattern.
Lin, Chi-San Althon, Smith, Tony C.
core  

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

A Critique of Saul Kripke's "Wittgenstein on Rules and Private Language" [PDF]

open access: yes, 2008
In Wittgenstein on Rules and Private Language, Saul Kripke presents a controversial skeptical argument, which he attributes to Wittgenstein’s interlocutor in the Philosophical Investigations [PI].
Gitsoulis, Chrysoula
core  

Pragmatic Arguments

open access: yesPhilosophy, 1959
Sometimes we draw conclusions about a thing's existence or its value by considering what are thought to be its consequences. I shall say that an argument is pragmatic when it consists in estimating an action, or any event, or a rule, or whatever it may be, in terms of its favourable or unfavourable consequences; what happens in such cases is that all ...
openaire   +2 more sources

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

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