Results 161 to 170 of about 4,006,141 (333)
Institutional Design and the Predictability of Judicial Interruptions at Oral Argument [PDF]
Tonja Jacobi +2 more
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The Limits of Computer Science. Weizsäcker’s Argument
The main purpose of this paper, which takes the form of an essay, is an attempt to answer the question of the limits of artificial intelligence (AI). In the introductory section, we present the key milestones in AI development, both historical and future
Olszewski Adam
doaj +1 more source
Cognitive linguistics/stylistics enable specific insights into the sex / gender identity issues, primarily by their basic theoretical postulate – mind embodiment. The aim of this paper is to analyze how the concept of rape functions in one particular statement/argument.
openaire +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
“The Hard Problem of Consciousness” and Two Arguments for Interactionism
Vadim V. Vasilyev +1 more
openalex +2 more sources
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Epistemic graphs for representing and reasoning with positive and negative influences of arguments [PDF]
Anthony Hunter +2 more
openalex +1 more source
A Sanitation Argument for Clean Indoor Air: Meeting a Requisite for Safe Public Spaces [PDF]
Anthony Leonardi, Asit Kumar Mishra
openalex +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source

