Results 91 to 100 of about 728,973 (290)

Plural marking in argument supporting nominalizations [PDF]

open access: yes, 2008
This paper investigates the conditions under which Argument Supporting Nominalizations (ASNs) can receive plural marking. Under ASNs, we discuss deverbal nouns that express an event and preserve argument structure.
Alexiadou, Artemis   +2 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Thinking About the Ultimate Argument for Realism [PDF]

open access: yes, 2003
The aim of this paper is to rebut two major criticisms of the No-Miracles Argument for Realism. The first comes from Musgrave (1988). The second comes from Colin Howson (2000).
Psillos, Stathis
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Case Perspective in Professional Praxis and in its Reflexive Self-Appraisal: Some General Considerations based on an Empirical Example from the Field of Family Mediation

open access: yesForum: Qualitative Social Research, 2008
In this article it is argued that developing a specific case perspective is of crucial importance for professions. The argument proceeds in two steps: First, the structural elements that are associated with the use of the term "case" are explicated and ...
Kai-Olaf Maiwald
doaj  

Appraisal Resources in Chinese College Students' English Argumentative Writing

open access: yesJournal of Language Teaching and Research, 2016
Appraisal system is the new development of Halliday's interpersonal function, which is a very important parameter in argumentative writing since its purpose is to influence and convince readers. Directed by appraisal system, with UAM corpus tool for annotation and statistics, this paper carried out a comparative empirical research in interpersonal ...
openaire   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Computer Aided Design Appraisal - a Modest Experiment

open access: yes, 2004
The paper starts with a re-iteration of the concept of appraisal of digital prototypes during the early phases of the architectural design activity and with a summary of research and development from the early seventies to the current time, the use of ...
J. Petric, T.W. Maver
core  

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