Results 1 to 10 of about 5,616 (132)
Structure of face-centred icosahedral quasicrystals with cluster close packing. [PDF]
Acta Crystallogr A Found AdvUsing higher‐dimensional crystallography, a new 6D structure model is proposed for F‐type icosahedral quasicrystals with cluster close packing.A 6D structure model for face‐centred icosahedral quasicrystals consisting of so‐called pseudo‐Mackay and mini‐Bergman‐type atomic clusters is proposed based on the structure model of the Al69.1Pd22Cr2.1Fe6.8 3 ...
Yamada T, Takakura H, Yamamoto A.
europepmc +2 more sources
Recent Insights in Multi-Target Drugs in Pharmacology and Medicinal Chemistry. [PDF]
ChemMedChemThis review highlights the rationale behind multitarget drug design as a promising approach to address diseases with complex etiologies. By combining pharmacophore features from different single‐target drugs, multitarget compounds can interact with multiple biological targets simultaneously.
Cemali SH +7 more
europepmc +2 more sources
Gene Expression, Docking and Machine Learning in Malaria Drug Discovery: A Systematic Review. [PDF]
Biochem Res IntBackground Malaria remains a significant and worldwide health threat with increasing resistance to current treatments, stimulating the demand for innovative approaches in pursuing drug discovery. This systematic review integrates the progress made from 2014 through 2024 regarding molecular methods like gene expression profiling, molecular docking and ...
Dangana RS +4 more
europepmc +2 more sources
Long non-coding RNAs as key regulators of neurodegenerative protein aggregation. [PDF]
Alzheimers DementAbstract The characteristic events in neurodegenerative diseases (NDDs) encompass protein misfolding, aggregation, accumulation, and their related cellular dysfunction, synaptic function loss. While distinct proteins are implicated in the pathological processes of different NDDs, the process of protein misfolding and aggregation remains notably similar
Xu Q, Liu D, Zhu LQ, Su Y, Huang HZ.
europepmc +2 more sources
Dendritic Cell Migration: An Essential Step in Initiating Adaptive Immunity Across Tissues. [PDF]
Immunol RevABSTRACT Immune surveillance of tissues is primarily carried out by dendritic cells (DCs), which act as sentinels for the adaptive immune system. To accomplish this task, DCs migrate from tissues to regional lymph nodes, or from blood‐exposed regions of the spleen to the white pulp, to prime T cell responses. DC migration is a tightly regulated process
Olson EC, Williams A, Eisenbarth SC.
europepmc +2 more sources
Arguing with Images as Extended Cognition
Informal Logic, 2018 In this paper the role of images in argumentative settings is analyzed from a cognitive angle. In particular, the proposal of this paper is to see visual argumentation as a specific form of extended and distributed cognition.
Cristián Santibáñez
doaj +1 more source
Informal Logic’s Influence on Philosophy Instruction
Informal Logic, 2008 Informal logic began in the 1970s as a critique of then-current theoretical assumptions in the teaching of argument analysis and evaluation in philosophy departments in the U.S. and Canada. The last 35 years have seen significant developments in informal
J. Anthony Blair
doaj +1 more source
Informal Logic, 2018 : Despite being a new term, ‘fake news’ has evolved rapidly. This paper argues that it should be reserved for cases of deliberate presentation of (typically) false or misleading claims as news, where these are misleading by design. The phrase ‘by design’
Axel Gelfert
doaj +1 more source
Steering into the Skid: On the Norms of Critical Thinking
Informal Logic, 2017 Cognitive bias presents as a pressing challenge to critical thinking education. While many have focused on how to eliminate or mitigate cognitive bias, others have argued that these biases are better understood as result from adaptive reasoning ...
Jeffrey Maynes
doaj +1 more source
Whately on Arguments Involving Authority
Informal Logic, 2008 Richard Whately’s views of arguments involving authority are very different in his Elements of Rhetoric and his Elements of Logic. This essay begins by documenting these differences and wondering why they are.
Hans V. Hansen
doaj +1 more source