Results 21 to 30 of about 21,046,637 (158)
Aptamer and DNAzyme Based Colorimetric Biosensors for Pathogen Detection
Angewandte Chemie, Volume 137, Issue 4, January 21, 2025.Pathogen detection is crucial for preventing and managing health risks. This review consolidates the selection of functional nucleic acids (FNAs) for pathogen detection and the development of cost‐effective, simple diagnostic applications. It focuses on integrating FNAs with gold nanoparticles, polydiacetylenes, protein enzymes, G‐quadruplexes, and ...
Rudi Liu +3 more
wiley +2 more sources
Dendritic Cell Migration: An Essential Step in Initiating Adaptive Immunity Across Tissues
Immunological Reviews, Volume 337, Issue 1, January 2026.ABSTRACT Immune surveillance of tissues is primarily carried out by dendritic cells (DCs), which act as sentinels for the adaptive immune system. To accomplish this task, DCs migrate from tissues to regional lymph nodes, or from blood‐exposed regions of the spleen to the white pulp, to prime T cell responses. DC migration is a tightly regulated process
Eli C. Olson +2 more
wiley +1 more source
Transcriptional Regulation of Microglial Metabolic and Activation States by P2RY12
Glia, Volume 73, Issue 12, Page 2464-2482, December 2025.Main Points Transcriptionally, P2RY12‐deficient microglia show heightened metabolic activity, iron handling and oxidative stress at baseline. Upon LPS challenge, impaired glutathione antioxidant responses suggest increased vulnerability to ferroptosis. ABSTRACT Microglia are the resident immune cells of the CNS.
Aida Oryza Lopez‐Ortiz +9 more
wiley +1 more source
Cell Proliferation, Volume 58, Issue 11, November 2025.CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far +4 more
wiley +1 more source
, 2016 A signer narrates "Condorito de Oro" #6 (comic book, BC1-799.pdf)Sivia ...
core +1 more source
Innovative Wirkstoffe aus der antibakteriellen Forschung im Kampf gegen mikrobielle Resistenzen
Angewandte Chemie, Volume 137, Issue 10, March 3, 2025.Dieser Artikel gewährt einen Überblick über in den letzten drei Jahrzehnten untersuchte antibakteriellen Wirkstoffe. Aspekte der Herkunft, der zellulären Targetstrukturen, des antibakteriellen Wirkspektrums und dem Nachweis der Wirksamkeit in Tierstudien werden zusammen mit aktuellen Entwicklungen beleuchtet.
Roderich D. Süssmuth +3 more
wiley +1 more source
The Rationality of Legal Discourse in Habermas's Discourse Theory
Informal Logic, 2003 This paper argues that Habermas's conception of the rationality of moral and legal discussions has import for argumentation theorists interested in the rationality of public deliberations in politics and law.
Eveline T. Feteris
doaj +1 more source